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ProteomicsInvestigating N-terminal shedding of GPR125 in GPR125 overexpressing HEK293T cells using N- and C-terminal enrichment and different cleavage strategies
The study was conducted to elucidate potential cleavage sites of GPR125 which are known to undergo N-terminal shedding through autoproteolysis in a region different to other GRPs. To do these different enzymatic strategies as well as enrichment of both N-terminal and C-terminal peptides, was conduct...
ORGANISM(S): Homo sapiens (Human) 
2026-08-31 | PXD083139 | Pride
Gpr125 Scx C-terminal Lysate Hek293t Enrichment Lc-msms Adra3 N-terminal Medium 
GenomicsGpr125 is a Unifying Hallmark of Multiple Mammary Progenitors coupled with Tumor Latency
Gpr125 is a Unifying Hallmark of Multiple Mammary Progenitors coupled with Tumor Latency
PRJNA786219 | ENA
TranscriptomicsGpr125 is a Unifying Hallmark of Multiple Mammary Progenitors coupled with Tumor Latency
Several markers have been used to identify mammary stem cell subpopulations. However, a specific unifying hallmark of progenitors has not yet been identified yet. Here we show the orphan adhesion G-protein coupled receptor, Gpr125, identifies and locates long-lived progenitors at multiple sites and ...
ORGANISM(S): Mus musculus 
2022-01-27 | GSE190180 | GEO
UnknownGpr125 modulates Dishevelled distribution and planar cell polarity signaling.
Not available
S-EPMC3699285 | biostudies-literature
UnknownArrestin-independent constitutive endocytosis of GPR125/ADGRA3.
Not available
S-EPMC6899654 | biostudies-literature
UnknownGpr125 Marks Distinct Cochlear Cell Types and Is Dispensable for Cochlear Development and Hearing.
Not available
S-EPMC8355630 | biostudies-literature
UnknownGPR125 positively regulates osteoclastogenesis potentially through AKT-NF-κB and MAPK signaling pathways.
Not available
S-EPMC8990458 | biostudies-literature
UnknownElevated G-Protein Receptor 125 (GPR125) Expression Predicts Good Outcomes in Colorectal Cancer and Inhibits Wnt/β-Catenin Signaling Pathway.
Not available
S-EPMC6225730 | biostudies-literature
UnknownEvaluation of candidate spermatogonial markers ID4 and GPR125 in testes of adult human cadaveric organ donors.
Not available
S-EPMC4153397 | biostudies-literature
UnknownGPR125 (ADGRA3) is an autocleavable adhesion GPCR that traffics with Dlg1 to the basolateral membrane and regulates epithelial apicobasal polarity.
Not available
S-EPMC9539791 | biostudies-literature
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