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PGRMC1 is a protein from the MAPR family with a range of cellular functions. PGRMC1 has been described to play a role in regulating membrane trafficking and in cancer progression and response to therapies. To further understand the functions of PGRMC1 and the mechanism of the small molecule inhibito...
ORGANISM(S): Homo sapiens (Human) 
2020-01-24 | PXD016455 | Pride
We analyzed the transcriptional response of the actinomycete Rhodococcus aetherivorans I24 to biphenyl and polychlorinated biphenyls (PCBs). This species has not been extensively exposed to PCBs, as it was first isolated from a toluene contaminated aquifer, rather than a site contaminated with polyc...
ORGANISM(S): Rhodococcus aetherivorans 
Combined menopausal hormone therapy is associated with increased breast cancer risk in postmenopausal women. In our previous studies, progesterone receptor membrane component 1 (PGRMC1) was shown to play a role in progestins’ mode of action, resulting in enhanced proliferation of breast cancer cells...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD028537 | Pride
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