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Time-resolve proximity proteomics of tight junction. To understand how the tight junction belt is assembled and positioned, we combined APEX2 proximity proteomics of the main junctional scaffold protein ZO-1 with a calcium switch tissue formation assay.This combination allowed us to synchronize the ...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2024-05-22 | PXD052221 | Pride
Our aim was to identify Regenerating islet-derived (REG proteins in dogs. We annotated REG-family members in the canine genome and proteome, and identified one member of the REG3 subfamily, consequently termed REG3E by the Vertebrate Gene Nomenclature Committee. We verified REG3E gene expression usi...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2022-10-17 | PXD035694 | Pride
Objective: Aging and early degeneration of the intervertebral disc (IVD) involves the substition of notochordal cells (NCs) in the nucleus pulposus (NP) by chondrocyte-like cells (CLCs). This study investigated the gene expression profiles involved in this process using NP tissue from both non-chond...
ORGANISM(S): Canis lupus familiaris 
The creation of a microvilli-rich apical luminal domain is essential for epithelial tissue morphogenesis and is closely coordinated with the formation of the apical junctional complex (AJC). De novo lumenogenesis, in which epithelial cells establish apical identity by directing apical cargo to an ap...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2026-06-08 | PXD061234 | Pride
Quantification and characterisation of canine hepcidin by LC-MS
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2020-05-26 | PXD015661 | Pride
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