Sort   by:  
 Page size 
ProteomicsThe C-terminal end of engineered albumin variants and fusion proteins after exposure to carboxypeptidase A
Albumin has a long plasma half-life due to engagement of the neonatal Fc receptor (FcRn), which prevents intracellular degradation. However, its C-terminal end can be cleaved by carboxypeptidase A, and removal of the last leucine residue (L585) weakens receptor binding, reducing its half-life from 2...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-05-19 | PXD063561 | Pride
Albumin engineering Carboxypeptidase a The neonatal fc receptor (fcrn) Albumin-fusion proteins 
ProteomicsIdentification of a Zinc Carboxypeptidase in a crude lysate SDS-PAGE gel of a Porphyromonas gingivalis transcription regulator mutant
Porphyromonas gingivalis is one of the main etiological agents responsible for the initiation and progression of periodontal diseases. This bacterium inhabits unfavorable conditions, therefore, to adapt to the changing external environment, e.g. redox conditions, and nutrient limitations, it must re...
ORGANISM(S): Porphyromonas gingivalis ATCC 33277 Bacteria 
2025-03-27 | PXD057991 | Pride
Mse Lc-ms Sds-page Crp/fnr protein superfamily Gel band analysis Transcription regulator mutant Putative zinc carboxypeptidase Bottom-up Porphyromonas gingivalis 
ProteomicsCarboxypeptidase B-assisted charge-based fractional diagonal chromatography for deep screening of C-terminome
The determination of protein C-termini is of great significance for protein function annotation and proteolysis re-search. However, the progress of C-terminomics is still far behind its counterpart, N-terminomics, because of the low reactivity of the carboxyl group. Herein, we developed a negative s...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2020-05-25 | PXD018520 | Pride
Chafradic Cleavage site C-terminomic Caspase 
TranscriptomicsCarboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.
They aim of the study is to identify targets of Carboxypeptidase E (CPE) as well as signaling cascades that are affected by CPE which are specific for transmitting its anti-migratory effects in glioma cells by overexpressing CPE and using transcriptomics profiling of mRNAs and microRNAs.
ORGANISM(S): Homo sapiens 
2017-11-29 | E-MTAB-5299 | biostudies-arrayexpress
TranscriptomicsCarboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.
They aim of the study is to identify targets of Carboxypeptidase E (CPE) as well as signaling cascades that are affected by CPE which are specific for transmitting its anti-migratory effects in glioma cells by overexpressing CPE and using transcriptomics profiling of mRNAs and microRNAs.
ORGANISM(S): Homo sapiens 
2017-11-29 | E-MTAB-5297 | biostudies-arrayexpress
MetabolomicsMicrobiome and metabolome profiles of severe versus mild influenza A cases: A case-control study

Background: Influenza A virus (IAV) causes a wide spectrum of clinical outcomes, from mild symptoms to life-threatening pneumonia. Recent studies have highlighted the role of the upper respiratory tract (URT) microbiota in modulating immune responses and influencing disease sever...

2025-11-03 | MTBLS13112 | MetaboLights
ProteomicsUncovering the Glutamate Carboxypeptidase II Microenvironment Using a Multi-labeling Proteomic Approach
Glutamate carboxypeptidase II (GCPII) is a membrane-bound metallopeptidase predominantly expressed in neural and prostatic tissues, with significantly elevated levels in prostate carcinoma that increase with tumor grade. Despite its significance as a target for imaging and therapy in prostate cancer...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD068378 | Pride
Μmap Psma Riboflavin Ibody Hrp Protein proximity labeling 
GenomicsAortic carboxypeptidase-like protein potentiates β1 integrin signaling in mesenchymal progenitors (10T1/2 fibroblasts)
Aortic carboxypeptidase-like protein potentiates β1 integrin signaling in mesenchymal progenitors (10T1/2 fibroblasts)
PRJNA1372083 | ENA
ProteomicsMechanisms of Resistance to Prostate-Specific Membrane Antigen-Targeted Radioligand Therapy in a Mouse Model of Prostate Cancer
Purpose: Prostate-specific membrane antigen-targeted radioligand therapy (PSMA-RLT) is effective against prostate cancer (PCa), but all patients relapse eventually. Poor understanding of the underlying resistance mechanisms represents a key barrier to development of more effective RLT. We investigat...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-04 | MSV000086408 | MassIVE
GenomicsAortic carboxypeptidase-like protein potentiates β1 integrin signaling in mesenchymal progenitors (Primary stromal cells)
Aortic carboxypeptidase-like protein potentiates β1 integrin signaling in mesenchymal progenitors (Primary stromal cells)
PRJNA1438046 | ENA
Sort   by:  
 Page size