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ProteomicsHistidine methylation of MYLK2 and C3H zinc fingers by CARNMT1
We here describe our independent uncovering of CARNMT1 as a protein histidine methyltransferase (HMT), and our extensive efforts on defining its substrate specificity and methylation targets. We found that recombinant CARNMT1 methylated MYLK2-derived peptide containing His-148 in vitro. The recombin...
ORGANISM(S): Homo sapiens (Human) Caenorhabditis elegans 
2025-07-28 | PXD060821 | Pride
C3h zinc finger 1mh 1-methylhistidine Mylk2 Spliceosome Histidine methyltransferase Rnf113a Protein methylation Carnmt1 U2af1 
GenomicsTranscriptome analysis of CARNMT1 knockout tissue
Transcriptome analysis of CARNMT1 knockout tissue
PRJNA952007 | ENA
GenomicsTranscriptome analysis of CARNMT1 knockout cells
Transcriptome analysis of CARNMT1 knockout cells
PRJNA901866 | ENA
TranscriptomicsTranscriptome analysis of CARNMT1 knockout tissue
Histidine (His) residues are methylated in various proteins, but their roles and regulation mechanisms remain unknown. Here, we showed that CARNMT1, a known His methyltransferase of dipeptide carnosine (βAla-His), is the major protein His N-position-specific methyltransferase. ProSeAM labeling and p...
ORGANISM(S): Mus musculus 
2023-09-06 | GSE228894 | GEO
ProteomicsProSeAM SILAC MS screening for CARNMT1 substrates
Click chemistry based substrates screening for CARNMT1 in Carnmt1 KO HEK293T cells.
ORGANISM(S): Homo Sapiens (human) 
2023-08-24 | PXD037965 | JPOST Repository
TranscriptomicsTranscriptome analysis of CARNMT1 knockout cells
Examination of transcriptome of CARNMT1 knockout cells by Ribosomal RNA depleted RNA-Seq
ORGANISM(S): Homo sapiens 
2023-09-06 | GSE217990 | GEO
UnknownHistidine N1-position-specific methyltransferase CARNMT1 targets C3H zinc finger proteins and modulates RNA metabolism.
Not available
S-EPMC10546975 | biostudies-literature
UnknownIdentification of substrates and sequence requirements for CARNMT1-mediated histidine methylation of C3H zinc fingers.
Not available
S-EPMC12275196 | biostudies-literature
UnknownMolecular basis for histidine N1 position-specific methylation by CARNMT1.
Not available
S-EPMC5938892 | biostudies-literature
UnknownMetabolic labeling based methylome profiling enables functional dissection of histidine methylation in C3H1 zinc fingers.
Not available
S-EPMC11358137 | biostudies-literature
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