We here describe our independent uncovering of CARNMT1 as a protein histidine methyltransferase (HMT), and our extensive efforts on defining its substrate specificity and methylation targets. We found that recombinant CARNMT1 methylated MYLK2-derived peptide containing His-148 in vitro. The recombin...
ORGANISM(S): Homo sapiens (Human) Caenorhabditis elegans
Studying and investigating the expression of KANSL3, KIF4A, and MYLK2 genes in women's clinical trials as functional biomarkers for predicting and screening the occurrence of breast cancer.
Donepezil, an acetylcholinesterase (AChE) inhibitor, was approved by FDA for the symptomatic therapies of patients with Alzheimer’s disease (AD) in 1996. Although donepezil have been regarded as the standard and first-line treatment for AD, the capacity of such drugs to alter the underlying disease ...
