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Venoms are a rich source for the discovery of molecules with biotechnological applications, but their analysis is challenging even for state-of-the-art proteomics. Here we report on a large-scale proteomic assessment of the venom of Loxosceles intermedia, the so-called brown spider. Venom of 200 sp...
ORGANISM(S): Loxosceles intermedia 
2017-05-16 | PXD005523 | Pride
Here's a suggested Project Description for your PRIDE submission: Project Description This dataset contains mass spectrometry raw files used as training data for SpecFormer, a transformer-based ion intensity prediction model integrated within PatternLab for Proteomics (Spectral Cruncher module). Th...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-02-16 | PXD069898 | Pride
Background: Obesity is characterized as a disease that directly affects the whole-body metabolism and is associated with excess fat mass and several related comorbidities. Dynamics of the adipocyte hypertrophy and hyperplasia play an important role in health and disease, especially in obesity. Human...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD026299 | Pride
Human peripheral blood mononuclear cells (PBMC) are key to several diagnostics assays and basic science research. Blood pre-analytical variations that occur before obtaining the PBMC fraction can have a significant impact on the results of the assays, including viability, composition, integrity, and...
ORGANISM(S): Homo sapiens (Human) 
2020-12-14 | PXD021367 | Pride
The continuous search for natural products that attenuate age-related losses has increasingly gained notice; among them, those applicable for skin care have drawn major attention. The bioester generated from the Chenopodium quinoa’s oil is a natural-origin ingredient described to produce replenishin...
ORGANISM(S): Homo sapiens (Human) 
2020-11-17 | PXD020893 | Pride
Chemical cross-linking has emerged as a powerful approach for the structural characterization of proteins and protein complexes. However, the correct identification of covalently linked (cross-linked) peptides analyzed by tandem mass spectrometry is still an open challenge. Here we present SIM-XL, a...
ORGANISM(S): Homo sapiens (Human) 
2015-02-02 | PXD001677 | Pride
Meningiomas are among the most common primary tumors of the central nervous system (CNS) and originate from the arachnoid or meningothelial cells. Risk factors for the disease include exposure to ionizing radiation, head trauma, and family history. Surgery is the first option of treatment for mening...
ORGANISM(S): Homo sapiens (Human) 
2020-06-30 | PXD015979 | Pride
Photoaging is the premature aging of the skin caused by prolonged exposure to solar radiation. The visual alterations manifest as wrinkles, reduced skin elasticity, uneven skin tone, as well as other signs that surpass the expected outcomes of natural aging. Beyond these surface changes, there is a ...
ORGANISM(S): Homo sapiens (Human) 
2024-04-04 | PXD045887 | Pride
We investigated the effects of a quinoa bioester in topical formulations on skin aging. Sixty-one female participants, one for each age between 20 and 80 years, with Fitzpatrick skin types IV or lower, underwent a 30-day treatment on the volar forearm. Skin samples were collected before and after tr...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD062216 | Pride
Professional drivers represent an ideal cohort for investigating the effects of solar radiation on skin due to their unique, asymmetric exposure to sun, a consequence of vehicle window orientations. Consequently, one side of the face is naturally subjected to more solar radiation, resulting in uneve...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD050746 | Pride
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