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ProteomicsAnalysis of proteotype, cell growth and metabolic changes induced by caspase-9 inhibition in chondrogenic cells
Caspase-9 is the major apical caspase responsible for triggering the intrinsic apoptotic pathway. Our pilot study indicated that specific inhibition of caspase-9 caused microscopically evident alterations in appearance of the primary chondrogenic cultures which cannot be explained by decrease in apo...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-03 | PXD034025 | Pride
Metabolism Proteomics Ms3 Dia Chondrogenesis Diapasef Caspase-9 Micromass cultures Itraq 
ProteomicsCaspase-9 is a positive regulator of osteoblastic cell migration identified by diaPASEF proteomics
Caspase-9 is traditionally considered as the initiator caspase of the intrinsic apoptotic pathway. In the last decade, however, other functions beyond initiation/execution of cell death have been described including cell type-dependent regulation of proliferation, differentiation/maturation, mitocho...
ORGANISM(S): Mus musculus (Mouse) 
2024-04-17 | PXD045703 | Pride
Mc3t3-e1 Osteoblast Caspase-9 Migration Diapasef 
TranscriptomicsIdentification of cytokine signals regulated by Caspase-9
Genome-wide transcriptional profiles of the hematopoietic stem and progenitor cell (HSPCs)-enriched population derived from bone marrow chimeras reconstituted with Caspase-9 or Bak and Bax deficient fetal liver cells. Gene ontology analysis revealed changes in the expression of genes associated with...
ORGANISM(S): Mus musculus 
2014-11-03 | E-GEOD-57934 | biostudies-arrayexpress
ProteomicsLegionella pneumophila effector LegK3 directly phosphorylates multiple caspases involved in apoptosis signaling, including Caspase-3, Caspase-7, and Caspase-9
Legionella pneumophila effector Legk3 phosphorylates caspase3/7/9 under infection, transfection, or in vitro purification condition
ORGANISM(S): Homo Sapiens 
PXD054358 |
TranscriptomicsIdentification of cytokine signals regulated by Caspase-9
Genome-wide transcriptional profiles of the hematopoietic stem and progenitor cell (HSPCs)-enriched population derived from bone marrow chimeras reconstituted with Caspase-9 or Bak and Bax deficient fetal liver cells. Gene ontology analysis revealed changes in the expression of genes associated with...
ORGANISM(S): Mus musculus 
2014-11-03 | GSE57934 | GEO
GenomicsCaspase 9-induced apoptosis for efficient fetal cell ablation and disease modeling
Caspase 9-induced apoptosis for efficient fetal cell ablation and disease modeling
PRJNA1187456 | ENA
UnknownCaspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9.
Not available
S-EPMC1925235 | biostudies-literature
UnknownTCR-induced, PKC-θ-mediated NF-κB activation is regulated by a caspase-8-caspase-9-caspase-3 cascade.
Not available
S-EPMC4107081 | biostudies-literature
UnknownNeurovascular injury associated non-apoptotic endothelial caspase-9 and astroglial caspase-9 mediate inflammation and contrast sensitivity decline.
Not available
S-EPMC9643361 | biostudies-literature
UnknownDeorphanizing Caspase-3 and Caspase-9 Substrates In and Out of Apoptosis with Deep Substrate Profiling.
Not available
S-EPMC9116730 | biostudies-literature
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