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Mammalian orthoreoviruses (reoviruses) are nonenveloped, double-stranded RNA viruses that assemble progeny particles in cytoplasmic viral factories (VFs) and exit some types of cells using a nonlytic release mechanism. In human brain microvascular endothelial cells (HBMECs), progeny reovirus virions...
ORGANISM(S): Homo sapiens (Human) Orthoreovirus 
2025-10-10 | PXD068971 | Pride
Asexual proliferation of the Plasmodium parasites that cause malaria follow a developmental program that alternates non-canonical intraerythrocytic replication with dissemination to new host cells. We carried out a functional analysis of the Plasmodium falciparum homolog of Protein Phosphatase 1 (Pf...
ORGANISM(S): Plasmodium falciparum Dd2 
2020-08-11 | PXD018718 | Pride
Toxoplasma gondii encodes three Protein Kinase A catalytic (PKAc1-3) and one regulatory (PKAr) subunits to integrate cAMP-dependent signals. Here, we show that inactive PKAc1 is maintained at the parasite pellicle by interacting with dually acylated PKAr. Either a conditional knockdown of PKAr or th...
ORGANISM(S): Toxoplasma gondii Toxoplasma gondii 
2017-10-12 | PXD006045 | Pride
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