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TranscriptomicsRNA-seq of control and CHH (cartilage-hair hypoplasia) fibroblasts transdifferentiated into chondrocytes-like cells
We used primary human CHH (cartilage-hair hypoplasia) and control fibroblasts in a chondrogenic transdifferentiation model (FDC; fibroblast-derived chondrocytes) to determine the chondrogenic capacity and differential pathway regulation of CHH cells. For the sequencing experiment, dermal fibroblasts...
ORGANISM(S): Homo sapiens 
2021-10-09 | E-MTAB-10996 | biostudies-arrayexpress
GenomicsrRNA 2'-O-methylation profile of SNORD71 knockdown cells
We generated a SNORD71 KO chondrocyte cell pool using CRISPR/Cas9 gene editing. A CRISPR control cell line was generated and used as a control. Levels of 2’-O-methylation of human rRNAs in SNORD71 KO cell pool and CRISPR control cells were evaluated by RiboMethSeq.
ORGANISM(S): Homo sapiens 
2022-03-05 | E-MTAB-11470 | biostudies-arrayexpress
TranscriptomicsRibosomal RNA 2’-O-methylation profile of human articular chondrocytes exposed to an osteoarthritic environment
We used chondrocytes exposed to osteoarthritic synovial fluid as a chronic disease model to study the effects of a chronic disease microenvironment on 2’-O-me rRNA heterogeneity. Human non-OA human articular chondrocytes (5 individual donors) were cultured either in the presence of OA-SF (20% (v/v),...
ORGANISM(S): Homo sapiens 
2022-03-05 | E-MTAB-11469 | biostudies-arrayexpress
ProteomicsRibosomal proteome of SW1353 cells cultured in the presence of the 10 ng/ml TGF-β3
Ribosomal proteome of SW1353 cells cultured in the presence of the 10 ng/ml TGF-β3 and control condition was assessed.
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD046114 | Pride
Ribosomal proteome Tgfb Sw1353 
ProteomicsCellular proteome of SW1353 cells cultured in the presence of the 10 ng/ml TGF-β3
Cellular proteome of SW1353 cells cultured in the presence of the 10 ng/ml TGF-β3 and control condition was assessed.
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD046111 | Pride
Yfgb Sw1353 Proteome 
ProteomicsSecretome of SW1353 cells cultured in the presence of the 10 ng/ml TGF-β3
Secretome of SW1353 cells cultured in the presence of the 10 ng/ml TGF-β3 and control condition was assessed.
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD046109 | Pride
Tgfb Sw1353 Secretome 
ProteomicsComparison of wild type and HSPG2+/- hiPSC-CMs
Investigating the effect of perlecan haploinsufficiency on cardiomyocyte differentiation
ORGANISM(S): Homo sapiens (Human) 
2025-02-26 | PXD046359 | Pride
Hspg2+/- Hipsc-cms 
ProteomicsProteomic analysis of equine tooth (pulp) ageing
This study investigates the proteomic profiles of horse tooth tissue, pulp, with a focus on the effects of age and disease. We analysed tissue samples from young, old, and diseased teeth to explore how ageing and disease influence protein expression across these dental tissues. The goal was to ident...
ORGANISM(S): Equus caballus (Horse) 
2026-05-13 | PXD067261 | Pride
Horse Tooth Ageing Lc-msms Pulp 
ProteomicsProteomic analyse of equine tooth (enamel) ageing
This study investigates the proteomic profiles of horse tooth tissues, including pulp, dentin, cementum, and enamel, with a focus on the effects of age and disease. We analyzed tissue samples from young, old, and diseased teeth to explore how aging and disease influence protein expression across the...
ORGANISM(S): Equus caballus (Horse) 
2026-05-13 | PXD065888 | Pride
Enamel Horse Tooth Ageing Lc-msms 
ProteomicsProteomic analyse of equine tooth (dentin) ageing
This study investigates the proteomic profiles of horse tooth tissues, including pulp, dentin, cementum, and enamel, with a focus on the effects of age and disease. We analyzed tissue samples from young, old, and diseased teeth to explore how aging and disease influence protein expression across the...
ORGANISM(S): Equus caballus (Horse) 
2026-05-13 | PXD065894 | Pride
Dentin Horse Tooth Ageing Lc-msms 
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