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The Cell Division Cycle and Apoptosis Regulator (CCAR) protein family members have recently emerged as regulators of alternative splicing and transcription, as well as having other key physiological functions. For example, mammalian CCAR2/DBC1 forms a complex with the zinc factor protein ZNF326 to i...
ORGANISM(S): Caenorhabditis elegans 
2024-02-26 | PXD043100 | Pride
Although apicomplexans lack conventional R-point regulators, presence of the quiescent G1 forms of 43 parasites, including mature T. gondii bradyzoites suggests that a functional RESTRICTION checkpoint 44 exists in apicomplexan parasites. We showed that Cdk-related G1 kinase TgCrk2 forms alternative...
ORGANISM(S): Toxoplasma gondii ME49 
2022-08-12 | PXD033109 | Pride
VEGFR2 (Vascular endothelial growth factor receptor 2) is a central regulator of placental angiogenesis. The study of the VEGFR2 proteome of chorionic villi at term revealed its partners MDMX (Double minute 4 protein) and PICALM (Phosphatidylinositol-binding clathrin assembly protein). Subsequently,...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD050049 | Pride
This paper presents the earliest documented evidence for the presence and consumption of horse meat in Early Bronze Age Sicily, significantly revising previous understandings of equid use on the island. Multidisciplinary analyses involving proteomics and lipidomics were performed on ceramic vessels ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD066335 | Pride
Cdc37 is a core cochaperone of the Hsp90 machinery. It is involved in an early stage of the chaperone cycle to activate nascent forms of protein kinases as well as to stabilize mature forms of a subset of protein kinases. Overall, the chaperone cycle is quite complex and involves several steps. Prog...
ORGANISM(S): Homo sapiens (Human) 
2018-01-22 | PXD008375 | Pride
Data from ProteomeXchange, 888 Proteomic analysis of microglial activation states, 1676 Microglial activation characterization. Experiment: BV2_IL102, file: folder summary. Published as part of Mol Cell Proteomics. 2015 Sep 30 . From the Abstract: {{i}} Microglia, the resident immune cells of the b...
ORGANISM(S): Mus_musculus_viruses, Mouse 
Data from ProteomeXchange, 888 Proteomic analysis of microglial activation states, 1676 Microglial activation characterization. Experiment: BV2_LPS_1, file: folder summary. Published as part of Mol Cell Proteomics. 2015 Sep 30 . From the Abstract: {{i}} Microglia, the resident immune cells of the b...
ORGANISM(S): Mus_musculus_viruses, Mouse 
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