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MetabolomicsEffects of hypoxic preconditioning on neuroblastoma tumour oxygenation and metabolic signature in a chick embryo model
Hypoxia episodes and areas in tumours have been associated with metastatic dissemination and poor prognosis. Given the link between tumour tissue oxygen levels and cellular metabolic activity, we hypothesised that the metabolic profile between metastatic and non-metastatic tumours would reveal poten...
2018-08-13 | MTBLS541 | MetaboLights
TranscriptomicsTranscriptional profiling by array of chick embryonic tissues: gastrulation, neural tube/notochord and limb development.
Microarray analysis of chick embryo tissues: Hamburger Hamilton (HH) stage 3+/4 and HH6 Hensen’s node, HH 3+/4 posterior primitive streak, notochord with ventral neural tube at HH10-11, dorsal neural tube at HH10-11 and anterior and posterior thirds of the wing bud at stages HH20-21 and HH24.
ORGANISM(S): Gallus gallus 
2016-08-23 | E-MTAB-4048 | biostudies-arrayexpress
ProteomicsApoptotic auditory brainstem of E13 chick embryo
We characterized the proteome of the auditory brainstem of a chick embryo on embryonic day 13, when apoptosis occurs in auditory nuclei. We identified caspase substrates by searching the peptidome for peptides C-terminal to caspase-typical cleavage sites.
ORGANISM(S): Gallus gallus (Chicken) 
2022-04-01 | PXD030697 | Pride
Auditory Chick Caspase Brainstem Apoptosis 
TranscriptomicsAnatomical and molecular dissection of the prestreak chick embryo
This paper shows detailed information of prestreak stage chick embryos at the morphological level by using scanning electron microscopy, and at the molecular level by RNAseq and expression analysis.
ORGANISM(S): Gallus gallus 
2020-02-12 | E-MTAB-7941 | biostudies-arrayexpress
TranscriptomicsBMP-mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors
The transition from progenitor to differentiated cells is critical for successful organogenesis; subtle alterations in this process can lead to developmental disorders. The anterior heart field (AHF) encompasses a niche in which cardiac progenitors maintain their multipotent and undifferentiated nat...
ORGANISM(S): Gallus gallus 
2010-08-01 | E-GEOD-19698 | biostudies-arrayexpress
TranscriptomicsAnalysis of retinoid targets in chick embryo wing buds
Chick wing buds at Hamburger and Hamilton stage 20 were treated with DMSO, all trans retinoic acid or synthetic retinoid EC23 via ion-exchange beads implanted into the wing buds. The anterior third of treated wing buds of surviving embryos were removed 24 hours after treatment by microdissection and...
ORGANISM(S): Gallus gallus 
2020-12-31 | E-MTAB-2545 | biostudies-arrayexpress
ProteomicsDeep Proteome of the Developing Chick Midbrain
The epithelial-to-mesenchymal transition (EMT) and migration of cranial neural crest cells are critical processes that occur in the early embryo that permit proper craniofacial patterning. Disruptions in these processes not only impair development but also lead to various diseases, underscoring the ...
ORGANISM(S): Gallus gallus (Chicken) 
2023-10-25 | PXD042200 | Pride
Midbrain Bottom-up proteomics Chick embryo Cranial neural crest Lc-ms/ms 
TranscriptomicsTranscription profiling during differentiation of the neural tube in HH stage 10 chick embryos
The spinal cord is generated progressively as cells leave the caudal region of the elongating body axis such that the temporal steps of neural differentiation become spatially separated along the head to tail axis. At key stages, it is therefore possible to isolate near-adjacent cell populations fro...
ORGANISM(S): Gallus gallus 
2014-08-01 | E-MTAB-2734 | biostudies-arrayexpress
GenomicsAnatomical and molecular dissection of the prestreak chick embryo
Anatomical and molecular dissection of the prestreak chick embryo
PRJEB32476 | ENA
TranscriptomicsGene signatures in wound tissue as evidenced by molecular profiling in the chicken embryo model
Modern functional genomic approaches may help to better understand the molecular events involved in tissue morphogenesis and to identify molecular signatures and pathways. We have recently applied transcriptomic profiling to evidence molecular signatures in the development of the normal chicken chor...
ORGANISM(S): Gallus gallus 
2010-05-27 | E-GEOD-21679 | biostudies-arrayexpress
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