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UnknownHousehold Immigration Status Had Differential Impact On Medicaid Enrollment In Expansion And Nonexpansion States.
Not available
S-EPMC5858580 | biostudies-literature
UnknownRandomized, Placebo-Controlled, Phase III Trial of Yeast-Derived Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Versus Peptide Vaccination Versus GM-CSF Plus Peptide Vaccination Versus Placebo in Patients With No Evidence of Disease After Complete Surgical Resection of Locally Advanced and/or Stage IV Melanoma: A Trial of the Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer Research Group (E4697).
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S-EPMC4669592 | biostudies-literature
ProteomicsCharacterization of PARP-6 function in knock out mice and patients with developmental delay
PARP-6, a member of a family of enzymes (17 in humans) known as poly-ADP- ribose polymerases (PARPs), is a neuronally enriched PARP. While previous studies from our group show that PARP-6 is a regulator of dendrite morphogenesis in hippocampal neurons, its function in the nervous system in vivo is p...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-21 | PXD025386 | Pride
Dendritic branching Parp-6  nervous system Marylation Bioid Spectral counts Adp-ribosylation Orbitrap fusion 
ProteomicsChemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets
Poly (ADP-ribose) polymerase 7 (PARP-7) has emerged as a critically important member of a large enzyme family that catalyze ADP-ribosylation in mammalian cells. PARP-7 is a critical regulator of the innate immune response. What remains unclear is the mechanism by which PARP-7 regulates this process,...
ORGANISM(S): Homo sapiens (Human) 
2021-07-21 | PXD020323 | Pride
Chemical genetics Marylation Parp-7 Protein-protein interactions Enzymatic targets 
ProteomicsS.wolfei membrane proteins - Membrane Complexes of Syntrophomonas wolfei Involved in Syntrophic Butyrate Degradation and Hydrogen Formation
Analyze S. wolfei membrane proteins separated on Blue Native gel bands
ORGANISM(S): Syntrophomonas wolfei 
2017-07-28 | PXD003633 | Pride
Wolfei Syntrophomonas Protein Membrane 
UnknownCabozantinib in progressive medullary thyroid cancer.
Not available
S-EPMC4164813 | biostudies-literature
ProteomicsChemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets
Poly(ADP-ribose) polymerase 7 (PARP7) has emerged as a critically important member of a large enzyme family that catalyze mono-ADP-ribosylation (MARylation) in mammalian cells. Unlike other PARPs, PARP7 is expressed in many different cell types and is upregulated by diverse stimuli, such as toxins, ...
ORGANISM(S): Homo sapiens (Human) 
2021-11-04 | PXD020340 | Pride
Adpr Ptm Post-translational modification Parp7 Adp-ribosylation 
ProteomicsComparative single-cell and spatial transcriptomics illuminate bat immunity and barrier tissue evolution
Bats have adapted to pathogens through diverse mechanisms, including increased resistance - rapid pathogen elimination, and tolerance - limiting tissue damage following infection. In the Egyptian fruit bat (an important model in comparative immunology) several mechanisms conferring disease toleranc...
ORGANISM(S): Rousettus aegyptiacus (Egyptian rousette) (Egyptian fruit bat) Mus musculus (Mouse) 
2024-11-18 | PXD058003 | Pride
Proteomics Bat Immunity Lc-ms/ms 
ProteomicsMetabolic Reprogramming Driven by Ant2 Deficiency Augments T Cell Function and Anti-Tumor Immunity
cell activation demands a significant boost in NAD+ levels, often outpacing the capacity of oxidative phosphorylation (OXPHOS). To explore how T cells manage this metabolic stress, we created T cell-specific ADP/ATP translocase-2 knockout (Ant2-/-) mice. Ant2, which is vital for ADP/ATP exchange bet...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-09 | PXD062646 | Pride
Naive t cells Mouse Ant2ko Spleen 
ProteomicsA microRNA/circle RNA axis promotes metastasis through CDR1-mediated anoikis-resistance
Lung cancer is an intrinsically highly metastatic disease and the leading cause of cancer-related deaths worldwide. Although discovery of molecular aberrations in lung adenocarcinomas has led to development of effective targeted therapies, corresponding “drivers” in lung squamous carcinomas (LUSC) h...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD012286 | Pride
Human Cdr1 Lung Cancer Squamous 
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