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TranscriptomicsExpression Profile of Primary Colorectal Cancers and associated Liver Metastases
Comparison of expression profiles of primary colorectal cancers with liver metastases of the same patient. Additionally, expression data of normal colon and liver tissue. Abstract of publication will be included upon publication Keywords: expression profiling, colorectal cancer, colon cancer, liver...
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-14297 | biostudies-arrayexpress
ProteomicsIdentification of a collagen marker in urine improves the detection of colorectal liver metastases
Previously, we reported that a combination of a collagen alpha-1(I) natural occurring peptide (NOP) AGPP(-OH)GEAGKP(-OH)GEQGVP(-OH)GDLGAP(-OH)GP (AGP) and serum carcinoembryonic antigen (CEA) has the potential to detect colorectal liver metastases (CRLM). The combined method needs to be adapted to i...
ORGANISM(S): Homo sapiens (Human) 
2019-11-15 | PXD013533 | Pride
Logistic regression model Colon cancer Colorectal cancer Prm Collagen Colorectal liver metastases Mass spectrometry Natural occurring peptides Urine 
TranscriptomicsComparative profiling of primary colorectal carcinomas and liver metastases
PURPOSE: We sought to identify genes of clinical significance to predict survival and the risk for colorectal liver metastasis (CLM), the most common site of metastasis from colorectal cancer (CRC). PATIENTS AND METHODS: We profiled gene expression in 31 specimens from primary CRC and 32 unmatched s...
ORGANISM(S): Homo sapiens 
2011-03-22 | E-GEOD-22834 | biostudies-arrayexpress
TranscriptomicsGenomic Profile of Primary Colorectal Cancers and associated Liver Metastases
Comparison of genomic alterations of primary colorectal cancers with liver metastases of the same patient Keywords: array CGH, colorectal cancer, colon cancer, liver metastasis 21 primary colorectal cancers and 21 matched liver metastases hybridized against sex-matched control pools
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-10179 | biostudies-arrayexpress
MetabolomicsFatty acid synthesis in colorectal cancer: characterization of lipid metabolism in serum, tumour, and normal host tissues
The objective of the experiment was to compare serum fatty acid metabolite abundance between individuals with varying clinical stages of colorectal cancer (stage I-IV) and age-and-gender matched disease-free controls. Fatty acid metabolite abundance was compared between locoregional (stage I-III) an...
2016-12-15 | MTBLS27 | MetaboLights
MetabolomicsPreoperative exercise induces anti-tumor Kupffer cells to prevent surgical stress-promoted colorectal cancer liver metastasis

Kupffer cells from both Sed and PEx mice were harvested for Metabolomics. 3 weeks after tumor injection, both mice bearing MC38 tumors were sacrificed. The livers were harvested and processed into single-cell suspensions, and KCs were isolated.

2025-12-09 | MTBLS13419 | MetaboLights
ProteomicsIdentification of a collagen marker in urine improves the detection of colorectal liver metastases
Previously, we reported that a combination of a collagen alpha-1(I) natural occurring peptide (NOP) AGPP(-OH)GEAGKP(-OH)GEQGVP(-OH)GDLGAP(-OH)GP (AGP) and serum carcinoembryonic antigen (CEA) has the potential to detect colorectal liver metastases (CRLM). The combined method needs to be adapted to i...
ORGANISM(S): Homo sapiens (Human) 
2019-11-15 | PXD013705 | Pride
Logistic regression model Colon cancer Colorectal cancer Prm Collagen Colorectal liver metastases Mass spectrometry Natural occurring peptides Urine 
TranscriptomicsWhole genome analysis for liver metastasis gene signitures in colorectal cancer
Liver metastasis is one of the major causes of death in colorectal cancer (CRC) patients. To understand this process, we investigated whether the gene expression profiling of matched colorectal carcinomas and liver metastases could reveal key molecular events involved in tumor progression and metast...
ORGANISM(S): Homo sapiens 
2008-01-31 | E-GEOD-6988 | biostudies-arrayexpress
ProteomicsDifferential regulation of extracellular matrix proteins in three recurrent liver metastases of a single patient with colorectal cancer
Colorectal cancer (CRC) patients suffer from the second highest mortality among all cancer entities. In half of all CRC patients, colorectal cancer liver metastases (CRLM) can be observed. Metastatic colorectal cancer is associated with poor overall survival and limited treatment options. Even after...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020109 | Pride
Ecm Prognostic factor Colorectal liver metastasis Crlm Proteomics Colorectal cancer Ecm signatures Metachronous liver metastasis Crc Extracellular matrix Lc-ms/ms 
ProteomicsA Non-interventional Clinical Trial Assessing Immune Responses After Radiofrequency Ablation of Liver Metastases From Colorectal Cancer
HLA ligandome analysis of colorectal adenocarcinoma tissues obtained from liver metastases (mCRC) as well as adjacent non-malignant liver tissues was performed to characterize the natural HLA class I and class II presented ligands on both mCRC and adjacent liver tissue.
ORGANISM(S): Homo sapiens (Human) 
2019-12-11 | PXD015947 | Pride
Neoplasia Cancer Hla-ligandomics Hla Colorectal adenocarcinoma Colon cancer Peptide Hla-restricted peptide Hla-ligand Colon Metastasis 
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