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In the malaria parasite Plasmodium falciparum, epigenetic modifications such as acetylation and methylation play important roles in parasite biology and virulence. Here, we characterised a new epigenetic mark, histone lactylation, recently discovered in humans and also present in Plasmodium. It was ...
ORGANISM(S): Plasmodium knowlesi strain H Plasmodium falciparum NF54 
2025-12-15 | PXD055236 | Pride
In Drosophila the chromosomal kinase JIL-1 is responsible for most interphase histone H3S10 phosphorylation and has been proposed to protect active chromatin from acquiring heterochromatic marks, like dimethylated histone H3K9 (H3K9me2) and HP1. Here, we show that JIL-1’s targeting to chromatin depe...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2019-10-09 | PXD012790 | Pride
Proteomics has been little used for the identification of novel prognostic and/or therapeutic markers in isocitrate dehydrogenase (IDH)-wildtype glioblastoma (GB). In this study, we analyzed 50 tumor and 30 serum samples from short- and long-term survivors of IDH-wildtype GB (STS and LTS, respective...
ORGANISM(S): Homo sapiens (Human) 
2024-07-04 | PXD045714 | Pride
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