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TranscriptomicsMetabolic features of Cryptosporidium parvum oocysts: Control vs. UV treatment.
Global gene expression in C. parvum environmental stage (oocysts) and the oocysts treated with UV comparing control untreated ones. Goal was to uncover the metabolic features in oocysts and the oocysts treated with UV. two-condition experiment, UV treatment vs. UV untreatment; two time points, 0.5h ...
ORGANISM(S): Cryptosporidium parvum 
2012-12-31 | E-GEOD-34307 | biostudies-arrayexpress
ProteomicsEnrichment and Proteomic Identification of Cryptosporidium parvum Oocyst Wall
The Cryptosporidium parvum (C. parvum) oocyst wall provides strong protection against hostile environmental factors; however, research is limited concerning about the oocyst wall at the proteomic level. In this study, a comprehensive analysis of the proteome expressed by the oocyst wall of C. parvum...
ORGANISM(S): Cryptosporidium parvum 
2022-10-05 | PXD029431 | Pride
Cryptosporidium parvum  oocyst wall  proteomics  detection 
ProteomicsA comprehensive proteome and the first phosphoproteome reveal extensive phosphorylation of carbohydrate metabolism in Cryptosporidium parvum sporozoites
Cryptosporidium parvum is an obligate intracellular apicomplexan parasite and a major cause of diarrheal disease in humans and animals. This dataset provides a comprehensive proteomic and phosphoproteomic resource for excysted C. parvum sporozoites, the invasive stage responsible for host cell entry...
ORGANISM(S): Cryptosporidium parvum x Cryptosporidium tyzzeri 
2026-09-28 | PXD079660 | Pride
Proteomics Dia Dia-pasef Cryptosporidium parvum Sporozoite Carbohydrate metabolism Phosphorylation Phosphoproteomics Glycolysis Lc-ms/ms 
TranscriptomicsTranscription profiling of human HCT-8 cells infected with Cryptosporidium parvum sampled at multiple time points with time seriess performed in triplicate
The origin of biological samples (In vitro infection of HCT-8 cells with Cryptosporidium parvum); Monolayers of the HCT-8 cells (ATCC CCL-244, American Type Culture Collection) were cultured in RPMI 1640 medium containing 10% fetal bovine serum and additional nutritional supplements. Cells in log ph...
ORGANISM(S): Homo sapiens 
2007-11-01 | E-GEOD-2077 | biostudies-arrayexpress
ProteomicsPost-translational modifications of vaccine candidates of Cryptosporidium parvum
Here we describe the post translational modifications on vaccine candidate proteins from Cryptosporidium parvum. We have identified O-glycosylated peptides from GP15, GP40, GP900, and a novel mucin-like protein referred to as GP20. In addition, we have discovered that the immune dominant antigen, C...
ORGANISM(S): Cryptosporidium parvum 
2017-08-14 | PXD005989 | Pride
Cryptosporidium parvum Lipopeptides Vaccine candidates Glycopeptides Lc-ms/ms 
TranscriptomicsMicroRNA profiling of human cholangiocyte H69 cells after infection with Cryptosporidium parvum
H69 cells were cultured in H69 medium with Cryptosporidium parvum oocysts(10 X 5 per well, for smaples 04, 05 and 06) or without oocysts(for samples 01, 02 and 03)for 8 hours and then collected for array analysis. Sample 07 was cells exposed to heated inactived oocysts.
ORGANISM(S): Homo sapiens 
2010-02-11 | E-MEXP-2050 | biostudies-arrayexpress
ProteomicsSpatial proteome map of Cryptosporidium parvum sporozoite
Cryptosporidium is a leading cause of diarrheal disease in children and an important contributor to early childhood mortality. The parasite invades intestinal epithelial cells and remodels them extensively including building an elaborate interface structure. How this occurs at the molecular level is...
ORGANISM(S): Cryptosporidium parvum virus 1 Cryptosporidium parvum Iowa II 
2023-03-30 | PXD038366 | Pride
Cryptosporidium Small granules Secretion Sps-ms3 Rhoptry Organelle Tmt Apicomplexa Hyperlopit Spatial proteome Dense granules Effectors Microneme 
ProteomicsExploring the glycosylation state of the Cryptosporidium parvum CpTSP protein family-HILIC glycopeptide enrichment
Cryptosporidium parvum is a zoonotic apicomplexan parasite and a common cause of diarrheal disease worldwide. The development of vaccines to prevent or limit infection remains an important goal for tackling these diarrheal diseases, which are a significant cause of infant morbidity in the developing...
ORGANISM(S): Cryptosporidium parvum Iowa II 
2023-01-12 | PXD023936 | Pride
Cryptosporidium Glycosylation Thrombospondin repeat 
GenomicsCryptosporidium parvum
Cryptosporidium parvum genetic crosses
PRJNA1263880 | ENA
ProteomicsExploring the glycosylation state of the Cryptosporidium parvum CpTSP protein family-FAIMS proteome
Cryptosporidium parvum is a zoonotic apicomplexan parasite and a common cause of diarrheal disease worldwide. The development of vaccines to prevent or limit infection remains an important goal for tackling these diarrheal diseases, which are a significant cause of infant morbidity in the developing...
ORGANISM(S): Cryptosporidium parvum Iowa II 
2023-01-12 | PXD023935 | Pride
Cryptosporidium Glycosylation Thrombospondin repeat 
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