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ProteomicsContext-dependent phosphorylation of CSDE1 drives interactions with ribosomes
The RNA-binding protein CSDE1 is a key regulator of mRNA stability and translation in a broad spectrum of biological processes. We have previously shown that CSDE1 functions as an oncoprotein promoting invasion and metastasis in melanoma, whereas it behaves as a tumour suppressor promoting cellular ...
ORGANISM(S): Homo sapiens (Human) 
2025-09-10 | PXD062774 | Pride
Csde1 Melanoma Phosphorylation 
ProteomicsIdentification of ubiquitination sites on protein CSDE1 in SHSY5Y cells.
This bottom-up proteomics dataset provides a global map of post-translational modifications (PTMs) on the RNA-binding protein CSDE1 in human neuroblastoma SHSY5Y cells. The data was acquired to survey the modification landscape of CSDE1, with a particular observation that lysine (K) residues display...
ORGANISM(S): Homo sapiens (Human) 
2026-03-02 | PXD073844 | Pride
Mkrn2 Csde1 Ubiquitination site 
ProteomicsCsde1 binds transcripts involved in protein homeostasis and controls their expression in erythropoiesis
The RNA binding protein Csde1 (Cold shock domain protein e1) is strongly upregulated during erythropoiesis, but its expression is reduced in Diamond Blackfan Anemia (DBA). To understand the role of Csde1 in DBA, and the cellular pathways controlled by Csde1 in erythropoiesis, we identified the trans...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-24 | PXD006358 | Pride
Proteomics Csde1 Label-free qauntification Ibaq Rna-binding protein Erythropoiesis Translation 
ProteomicsCo-immumnoprecipitation experiments to identify protein bindining partners of CSDE1
While the transcriptional network of human embryonic stem cells (hESCs) has been extensively studied, relatively little is known about how post-transcriptional modulations determine hESC function. RNA-binding proteins play central roles in RNA regulation, including translation and turnover. Here we ...
ORGANISM(S): Homo sapiens (Human) 
2018-05-16 | PXD007271 | Pride
Lc-ms Co-ip Hescs 
ProteomicsA post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells
While the transcriptional network of human embryonic stem cells (hESCs) has been extensively studied, relatively little is known about how post-transcriptional modulations determine hESC function. RNA-binding proteins play central roles in RNA regulation, including translation and turnover. Here we ...
ORGANISM(S): Homo sapiens (Human) 
2018-05-16 | PXD007270 | Pride
Shrna Lc-ms Hescs 
GenomicsProfiling of CSDE1-bound RNAs under MKRN2-mediated ubiquitination
Profiling of CSDE1-bound RNAs under MKRN2-mediated ubiquitination
PRJNA1415271 | ENA
UnknownStrap associates with Csde1 and affects expression of select Csde1-bound transcripts.
Not available
S-EPMC6107111 | biostudies-literature
GenomicsiCLIP transcriptome-wide mapping of UNR (CSDE1) binding sites
iCLIP transcriptome-wide mapping of UNR (CSDE1) binding sites
PRJEB10303 | ENA
UnknownCSDE1 promotes miR-451 biogenesis.
Not available
S-EPMC10516617 | biostudies-literature
UnknownCSDE1 stabilizes AGO2 in embryonic stem cells.
Not available
S-EPMC12851991 | biostudies-literature
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