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TranscriptomicsCX43 KO vs WT cortical astrocytes
RNA samples extracted from astrocytes cultured from wild type and Cx43 null neonatal mice were dye labeled and individually co-hybridized with a reference of labeled cDNAs pooled from a variety of tissues on eight gene arrays containing 8975 mouse DNA sequences
ORGANISM(S): Mus musculus 
2010-06-05 | E-GEOD-580 | biostudies-arrayexpress
ProteomicsNuclear Cx43 interactome LC-MSMS
Our research provides a robust rationale for the clinical investigation of Cx43 as a therapeutic target with the potential to enhance the efficacy of existing treatments, prevent the emergence of drug resistance, and address the key limitation of current targeted therapies.
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD053555 | Pride
Lc-msms Cx43 Interactome Nuclear Melanoma 
ProteomicsSecretome analysis of Cx43 expressing cells
Extracellular matrix remodeling, degradation and glioma cell motility are critical aspects of glioblastoma multiforme (GBM). Despite being a rich source of potential biomarkers and targets for therapeutic advance, the dynamic changes within the extracellular environment that are specific to GBM cell...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-04-17 | PXD012175 | Pride
Glioma Connexin Secretome Connexin43 
TranscriptomicsCX43 heterozygous, Cx43 null and Cx32 null vs wildtype neonatal mouse brain
Cy3-labeled cDNA from brains of neonatal C57BL Cx43 null, Cx43 heterozygous and Cx32 null mice were compared among themselves and to Cy3-labeled cDNA from brains of neonatal C57BL wildtype mice through Cy5-labeled sample reference prepared at once for the entire experiment from aorta, brain, heart, ...
ORGANISM(S): Mus musculus 
2010-06-05 | E-GEOD-1954 | biostudies-arrayexpress
ProteomicsCx43-interaction network in the heart
The main objective of the present report was to unravel the Cx43-interaction network in the heart, and to establish the impact of heart ischemia and I/R upon these interactions. In order to characterize the cardiac Cx43 interactome under ischemia and I/R, a quantitative proteomic analysis was perfor...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-09 | PXD002331 | Pride
Connexin43  interactome  cardiomyocytes  ap-swath 
GenomicsTargeting microglial Cx43 in Alzheimer's disease
Targeting microglial Cx43 in Alzheimer's disease
PRJNA1138724 | ENA
ProteomicsCx43 purified protein analysis (N-term analysis)
Purified Cx43 was analyzed to check for modifications of its N-terminus to aid structural studies.
ORGANISM(S): Homo sapiens (Human) 
2023-07-27 | PXD033824 | Pride
Dia Purified protein Lc-ms/ms 
TranscriptomicsConnexin43 null vs wildtype neonatal mouse HEART
Cy3-labeled cDNA obtained from four pools of three hearts of neonatal C57BL Cx43 null mice were compared to Cy3-labeled cDNA obtained from four pools of three hearts of neonatal C57BL wildtype mice through Cy5-labeled sample reference prepared at once for the entire experiment from aorta, brain, hea...
ORGANISM(S): Mus musculus 
2010-06-05 | E-GEOD-1961 | biostudies-arrayexpress
GenomicsCDH2 and Cx43 knockdown CSCs compaired with scramble (control) in breast cancer
CDH2 and Cx43 knockdown CSCs compaired with scramble (control) in breast cancer
PRJNA575855 | ENA
TranscriptomicsSertoli cell specific testicular gene expression of Connexin 43 knockout mice
Infertility observed in adult Sertoli cell (SC)-specific Connexin 43 Knockout-mice rather seems to be an effect of the disturbed SC-Germ cell (GC) crosstalk than a direct consequence of the loss of Cx43 protein in SC with important GC specific genes being mostly affected by this deletion. Identifica...
ORGANISM(S): Mus musculus 
2011-01-06 | E-GEOD-23431 | biostudies-arrayexpress
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