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ProteomicsExtracellular Vesicles from the Probiotic Yeast Pichia kudriavzevii: Proteomic Characterization and Modulation of Immune and Defense Responses in an Induced Inflammation Model of Intestinal Epithelial Cells
Extracellular vesicles (EVs) derived from probiotics represent a new and exciting frontier in host-microbe therapeutics. These nanoscale carriers are not merely cellular byproducts but are sophisticated mediators of intercellular communication, capable of modulating immune responses, reducing inflam...
ORGANISM(S): Pichia kudriavzevii 
2026-04-06 | PXD069498 | Pride
Probiotics  pichia kudriavzevii  membrane vesicles  proteomics  immuno-inflammatory responses 
ProteomicsExtracellular vesicles from Kluyveromyces marxianus as potential postbiotic against Candida albicans vaginal infections
A class of extracellular vesicles (EVs), isolated from the culture supernatant of a Kluyveromyces marxianus strain deriving from an artisanal sourdough, is reported. Previous work had clearly shown the probiotic properties of the yeast isolate, and its antagonistic activities against clinical flucon...
ORGANISM(S): Ascomycota Kluyveromyces marxianus 
2026-06-25 | PXD078607 | Pride
Probiotics Vulvo-vaginal candidiasis Biofilm Yeast 
ProteomicsProteomic elucidation of fructose-diet associated molecular alterations in hypothalamus of adolescent rats
The crucial role of nutrition for cerebral health and the impact of dietary habits on brain structure and function have been long far recognized. To date a major health concern is associated with the increased consumption of fructose as added sugar in many types of drinks and processed foods, especi...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-03-11 | PXD038834 | Pride
Hypothalamus Proteomics Mitochondria Inflammation. Adolescence Fructose-rich diet 
ProteomicsAPE1 INTERACTOME - Architecture of The Human Ape1 Interactome Defines Novel Cancers Signatures
The present work aimed at defining the association of the APE1-protein-protein interactions network in modulating its role in tumor progression and chemoresistance through proteomic and bionformatic analyses
ORGANISM(S): Homo sapiens (Human) 
2020-01-16 | PXD013368 | Pride
Nlc/ms/ms Interactome 
ProteomicsThe role of FKBP51 in the activation of Akt oncogenic pathway
FKBP51 is an immunophilin with a relevant role in sustaining cancer cell growth and aggressiveness, particularly in melanoma. Thanks to its scaffold and isomerase activities, mediated by its TPR and FK1 domains, respectively, FKBP51 participates in several signaling pathways. Akt is a serine-threoni...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD033828 | Pride
Lc-ms-ms Fkbp51 Interactome 
ProteomicsProteomic analysis of Limosilactobacillus reuteri DSM 17938
The aim of this work was to assess the antibiofilm activity of Cell Free Supernatant (CFS) produced by Limosilactobacillus reuteri DSM 17938 versus biofilm-producer bacterial species of clinical relevance.
ORGANISM(S): Escherichia coli 
2025-06-09 | PXD035326 | Pride
Extracellular membrane vesicles Postbiotics Lactobacillus reuteri Cytotoxicity  metabolomics Probiotics Limosilactobacillus reuteri Antibiofilm activity Cell free supernatant 
ProteomicsLow-protein/high carbohydrate diet
Low-protein/high carbohydrate (LP/HC) diet promotes metabolic health and longevity in adult human and animal models. However, the complex molecular underpinnings of how LP/HC diet leads to metabolic benefits remain elusive. Through a multi-layered approach, here we observed that LP/HC diet promotes ...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD017786 | Pride
Adipose tissue Diet 
ProteomicsDownregulation of RING ligase praja2 boosts receptor tyrosine kinases in kidney cancer
Clear cell renal cell carcinoma (ccRCC) is the most common variant of kidney cancer in the adult population. Late diagnosis, resistance to therapeutics and recurrence of metastatic lesions account for the highest mortality rate among kidney cancer patients. Identifying novel biomarkers for early can...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD034966 | Pride
Lc-ms-ms Praja2 Interactome 
ProteomicsProteomics analysis of Moringa oleifera Lam. miRNAs effects in HeLa cell lines on tumorigenesis and EMT
A concise and factual abstract is required. The abstract should state briefly the purpose of the research, the principal results and major conclusions. An abstract is often presented separately from the article, so it must be able to stand alone. For this reason, References should be avoided, but i...
ORGANISM(S): Homo sapiens (Human) 
2026-06-25 | PXD039475 | Pride
Plant mirnas  epithelial to mesenchymal transition  tumorigenesis  moringa oleifera lam  cross kingdom 
UnknownAmino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4).
Not available
S-EPMC3427085 | biostudies-literature
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