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UnknownCOVID-19 Vaccines Confer Protection in Hospitalized Pregnant and Postpartum Women with Severe COVID-19: A Retrospective Cohort Study.
Not available
S-EPMC9146232 | biostudies-literature
TranscriptomicsB cell-intrinsic STAT6 controls the germinal center response in type 2 immunity
By investigating the germinal center (GC) formation in STAT6ko/WT bone marrow-mixed chimera we found that GC formation in type 2 immune responses is dependent on B cell intrinsic expression of IL-4/IL-13-induced genes. We therefore used microarrays to find Stat6 dependent genes that are important fo...
ORGANISM(S): Mus musculus 
2014-05-26 | E-GEOD-47679 | biostudies-arrayexpress
ProteomicsADAM17 cytoplasmic domain modulates Thioredoxin-1 conformation and activity
We have demonstrated that site-directed mutagenesis in ADAM17 (ADAM17cytoF730A) also disrupts the interacting interface with Trx-1, resulting in a decrease of Trx-1 reductive capacity and activity. One of the mechanisms that explain this effect might be that ADAM17cyto favors Trx-1 monomerization st...
ORGANISM(S): Homo sapiens (Human) 
2020-10-19 | PXD015431 | Pride
Adam17 Thioredoxin-1 Mass spectrometry Redox signaling. Dimerization Iodotmt 
ProteomicsReductionist approach using primary and metastatic cell-derived extracellular vesicles prospect proteins associated with oral cancer prognosis
Oral squamous cell carcinoma (OSCC) shows high mortality rates that are largely associated with the presence of lymph node metastasis. However, the molecular mechanisms that drive OSCC metastasis are unknown. Here, we used a reductionist approach mapping the proteomic, miRNA, metabolomic and lipidom...
ORGANISM(S): Homo sapiens (Human) 
2021-07-19 | PXD019216 | Pride
Metabolomics Mirna Multi-omics approach Lipidomics Lymph node metastasis Extracellular vesicles Oral cancer squamous cell carcinoma Proteomics Prognosis 
UnknownGenomic characterization of a novel SARS-CoV-2 lineage from Rio de Janeiro, Brazil.
Not available
S-EPMC8139668 | biostudies-literature
ProteomicsHIV-1 Nef changes the proteome of T cells extracellular vesicles
Extracellular vesicles (EVs) are biomolecule carriers for intercellular communication in health and disease. Nef is a human immunodeficiency virus (HIV) virulence factor that is released from cells within EVs and is present in plasma EVs of HIV-1 infected individuals. We performed a quantitative pro...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2024-01-26 | PXD041028 | Pride
Hiv-1 Nef Exosomes Extracelular vesicles 
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