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TranscriptomicsshRNA-mediated knock down of Bmi-1 and Mel-18 in medulloblastoma cells
Bmi-1 and Mel-18 are close structural homologues that belong to the polycomb group (PcG) of transcriptional regulators of homeotic gene expression in development. They are believed to stably maintain repression of gene expression by altering the state of chromatin at specific promoters. A number of...
ORGANISM(S): Homo sapiens 
2007-10-31 | E-GEOD-7578 | biostudies-arrayexpress
ProteomicsLC-MS/MS analysis of Daoy and UW228 medulloblastoma cell lines
The goal of this study was to profile the total proteome and transcriptome of the established medulloblastoma cell lines, Daoy and UW228, using label-free nano-LC-MS/MS-based quantitative proteomics and high-throughput RNA sequencing (RNA-Seq), coupled with pathway analysis to identify differentiall...
ORGANISM(S): Homo sapiens (Human) 
2017-10-27 | PXD002659 | Pride
Medulloblastoma Daoy Uw228 Lc-ms/ms 
GenomicsCulturing of Daoy cells in astrocyte conditioned media
Culturing of Daoy cells in astrocyte conditioned media
PRJNA625003 | ENA
TranscriptomicsSynergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma (Daoy) cells
Aberrant activation of Hedgehog (HH) signaling has been identified as a key etiologic factor of many human malignancies. Signal strength, target gene specificity, and oncogenic activity of HH signaling profoundly depend on interactions with other pathways such as epidermal growth factor receptor-med...
ORGANISM(S): Homo sapiens 
2014-07-31 | E-GEOD-46045 | biostudies-arrayexpress
TranscriptomicsElevating Sox2 levels deleteriously affects the growth of glioblastoma and medulloblastoma cells.
Induction of the transcription factor Sox2 from a doxycycline-inducible promoter in iSox2-DAOY medulloblastoma cells. Affymetrix microarrays were used to characterize the gene expression profile of iSox2-DAOY cells in the absence and presence of doxycycline. Human DAOY medulloblastoma cells were eng...
ORGANISM(S): Homo sapiens 
2012-08-25 | E-GEOD-36947 | biostudies-arrayexpress
GenomicsExpression profile of shNT and shPTX3 DAOY cells
Expression profile of shNT and shPTX3 DAOY cells
PRJNA1369457 | ENA
Proteomicsrole of LIN28B protein in medulloblastoma by siRNA-mediated silencing of LIN28B in Daoy cells
To understand the role of LIN28B protein in medulloblastoma by siRNA-mediated silencing of LIN28B in Daoy cells and analysing the differentially-regulated proteins and pathways.
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD022481 | Pride
Medulloblastoma Sirna Lin28b 
ProteomicsBioID proximity labelling of MAP4K4 interactors in DAOY medulloblastoma cells
Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) is Ser/Thr protein kinase highly expressed in medulloblastoma (MB) patient samples which promotes cell migration and invasiveness downstream of growth factor receptors. Although MAP4K4 implication in the control of the membrane protrus...
ORGANISM(S): Homo sapiens (Human) 
2022-08-04 | PXD031870 | Pride
Bioid Medulloblastoma Map4k4 
TranscriptomicsRole of MXD3 in DAOY cell proliferation
This SuperSeries is composed of the following subset Series: GSE34050: ChIP-chip from DAOY cells stably expressing HA-MXD3 with anti-HA GSE34100: Expression profiling of MXD3 stable cell lines Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-07-12 | E-GEOD-34101 | biostudies-arrayexpress
UnknownRole of MXD3 in proliferation of DAOY human medulloblastoma cells.
Not available
S-EPMC3393725 | biostudies-literature
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