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ProteomicsLC-MS/MS analysis of Daoy and UW228 medulloblastoma cell lines
The goal of this study was to profile the total proteome and transcriptome of the established medulloblastoma cell lines, Daoy and UW228, using label-free nano-LC-MS/MS-based quantitative proteomics and high-throughput RNA sequencing (RNA-Seq), coupled with pathway analysis to identify differentiall...
ORGANISM(S): Homo sapiens (Human) 
2017-10-27 | PXD002659 | Pride
Medulloblastoma Daoy Uw228 Lc-ms/ms 
ProteomicsCo-IP interactome studies of FRS2/B7-H3 ± C7/Chloroquine in UW228 cells
Fibroblast growth factor receptor substrate 2 (FRS2) and B7-H3/CD276 are both highly expressed in medulloblastoma (MB) patient samples. While FRS2 has been shown to drive an invasive tumor phenotype, the biological role of B7-H3/CD276 is still incompeletely understood. Here, we explored the interact...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD062611 | Pride
Pediatric Chloroquine Co-immunoprecipitation Medulloblastoma C7 B7-h3 Uw228 Cd276 Brain cancer Frs2 
UnknownIntegrated Proteomic and Transcriptomic-Based Approaches to Identifying Signature Biomarkers and Pathways for Elucidation of Daoy and UW228 Subtypes.
Not available
S-EPMC5372226 | biostudies-literature
ProteomicsAPEX2 proximity labelling of FRS2 interactors in UW228 cells
The scaffold protein FRS2 is overexpressed in medulloblastoma (MB) and correlates with aggressive tumor phenotype and poor prognosis. Studies regarding FRS2's interactome have been limited to the assembly of the well described canonical FGFR signalosome. Here, we explored the proteomic proximity of ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD062524 | Pride
Human Medulloblastoma Interactors Apex2 Frs2 
UnknownMedullospheres from DAOY, UW228 and ONS-76 cells: increased stem cell population and proteomic modifications.
Not available
S-EPMC3663798 | biostudies-literature
TranscriptomicsGenome-wide gene expression profile of human medulloblastoma cell lines
To study the effect of constitutive REST expression on DAOY, UW228 and UW426 cells, we generated low and high-REST (LR/HR) isogenic pairs of the three human medulloblastoma (MB) cell lines and performed RNA-Seq analysis. We also analyzed the expression profiles of D283 cells (Group3/4 MB cell line) ...
ORGANISM(S): Homo sapiens 
2021-01-16 | GSE164887 | GEO
UnknownCRABP-II methylation: a critical determinant of retinoic acid resistance of medulloblastoma cells.
Not available
S-EPMC5528385 | biostudies-literature
UnknownResveratrol Reverses Retinoic Acid Resistance of Anaplastic Thyroid Cancer Cells via Demethylating CRABP2 Gene.
Not available
S-EPMC6828648 | biostudies-literature
UnknownCombination of PARP and WEE1 inhibitors in vitro: Potential for use in the treatment of SHH medulloblastoma.
Not available
S-EPMC10196712 | biostudies-literature
UnknownB7-H3 in Medulloblastoma-Derived Exosomes; A Novel Tumorigenic Role.
Not available
S-EPMC7583814 | biostudies-literature
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