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TranscriptomicsPseudomonas aeruginosa two-component regulator BfmR controls bacteriophage lysis and DNA release during biofilm development through PhdA
Biofilms are surface-adhered bacterial communities encased in an extracellular matrix composed of polysaccharides, proteins, and extracelluar (e)DNA, with eDNA being required for the formation and integrity of biofilms. Here we demonstrate that the spatial and temporal release of eDNA is regulated b...
ORGANISM(S): Pseudomonas aeruginosa 
2011-06-01 | E-GEOD-28953 | biostudies-arrayexpress
ProteomicsHypoxia promotes the generation of a versican-rich extracellular matrix by human coronary artery endothelial cells
• Exposure of endothelial cells (HCAECs) to hypoxia alters gene an protein expression • Genes and proteins related to endothelial dysfunction and activation are overexpressed • Hypoxia induces a versican-rich matrix with an altered glycosaminoglycan profile • This modified matrix perturbs cell adhes...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD052078 | Pride
Ecm Hypoxia Proteomics 
UnknownPhosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.
Not available
S-EPMC4769169 | biostudies-literature
UnknownCharacteristic Cytokine and Chemokine Profiles in Encephalitis of Infectious, Immune-Mediated, and Unknown Aetiology.
Not available
S-EPMC4726626 | biostudies-literature
UnknownProgressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice.
Not available
S-EPMC4526103 | biostudies-literature
ProteomicsMass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancer

Filip Mundt, Sandeep Rajput, Shunqiang Li, Kelly Ruggles, Arshag D. Mooradian, Philipp Mertins, Michael A. Gillette, Karsten Krug, et al., Cancer Res. 2018 May 15;78(10):2732-2746. doi: 10.1158/0008-5472.CAN-17-1990.

Activation of phosphoinositide 3-kinase (PI3K) signaling is frequently obs...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-10-19 | MSV000083050 | MassIVE
ProteomicsGeneration of aggregates of alpha-lactalbumin by UV-B light exposure
Whey proteins are widely used as ingredients in the form of aggregates to obtain certain functionalities in food applications. The aim of this study was to understand how UV illumination generates aggregates of alpha-lactalbumin (a-LA) as an alternative to heat treatments traditionally used for indu...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) 
2019-12-16 | MSV000084695 | MassIVE
UnknownDiversity and Scale: Genetic Architecture of 2,068 Traits in the VA Million Veteran Program.
Not available
S-EPMC10327290 | biostudies-literature
ProteomicsProteogenomics Connects Somatic Mutations to Signalling in Breast Cancer
Explore This Study at the NCI Proteomic Data Commons

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-28 | MSV000084248 | MassIVE
ProteomicsProteogenomic Integration Reveals Therapeutic Targets in Breast Cancer Xenografts
Huang K, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, et al., (2017) Nature Communications | 8:14864 | DOI: 10.1038/ncomms14864 | http://www.nature.com/articles/ncomms14864

Recent advances in mass spectrometry (MS) hav...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-28 | MSV000084249 | MassIVE
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