Sort   by:  
 Page size 
ProteomicsAn Investigation of the Altered Textural Property in Woody Breast Myopathy Using an Integrative Omics Approach
The functionality/integrity of sarcoplasmic reticulum was compared between normal vs. myopathic woody breast tissues in Gallus gallus. Shotgun MS profiling of protein expression revealed an upregulation of calcium transport proteins and a downregulation of proteins responsible for calcium release. ...
ORGANISM(S): Gallus gallus (Chicken) 
2022-05-19 | PXD031445 | Pride
Woody breast myopathy in gallus gallus Sarcoplasmic reticulum Dda shotgun profiling on fusion ms Calcium signalling Maxquant 
ProteomicsHuman plasma LC-MS/MS from children with bacterial and viral infections
LC-MS/MS proteomic profiling was performed on children with bacterial and viral infections using plasma samples. Protein biomarkers indiciative of bacterial or viral infection were identified.
ORGANISM(S): Homo sapiens (Human) 
2023-11-14 | PXD042003 | Pride
Lc-ms/ms Human Plasma 
ProteomicsHuman plasma LC-MS/MS from children with bacterial and viral infections
LC-MS/MS proteomic profiling was performed on children with bacterial and viral infections using plasma samples. Protein biomarkers indiciative of bacterial or viral infection were identified.
ORGANISM(S): Homo sapiens (Human) 
2023-11-14 | PXD041960 | Pride
Viral Bacterial Plasma Humans Lc-ms/ms 
ProteomicsSimple and efficient micro-SPE tip-based sample preparation workflow to enable sensitive proteomic profiling of limited samples
In-depth LC-MS-based proteomic profiling of limited samples has been problematic due, in large part, to the inefficiency of sample preparation and attendant sample losses. To address this issue, we developed On-Micro Solid-phase Extraction Tip-based (OmSET) sample preparation for limited biological...
ORGANISM(S): Homo sapiens (Human) 
2021-02-23 | PXD022313 | Pride
Micro-spe tip Omset Limited sample On-micro solid-phase extraction tip Sample preparation Stagetip 
ProteomicsLKB1/STK11-sensing of mitochondrial function controls Th17 cell responses
T helper 17 (Th17) cells are a distinct subset of CD4+ T cells necessary for maintaining gut homeostasis and have prominent roles in autoimmunity and inflammation. Th17 cells have unique metabolic features, including a stem cell-like signature and reliance on mitochondrial respiratory chain function...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD036162 | Pride
Dia Spectronaut Th17 t cells Serine/threonine kinase liver associated kinase b1 (lkb1/stk11). Opa1 knock out th17 cells 
ProteomicsImpaired M2 macrophage polarization in aging shifts the lipidome to pro-inflammatory mediators driving chronic inflammation and impairing tissue maintenance
Inflammation is the natural defensive response of the immune system to an injury or infection and is regulated by small molecule mediators triggering different phases of the inflammatory process. In particular, lipid mediators (LM) and cytokines exhibit crucial regulatory functions in the progressio...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD027357 | Pride
Immune system Macrophages Differentiation Mouse Aging 
Proteomics: Robust and reproducible large-scale label-free deep quantitative profiling of the MOLM-14 surfaceome using three mass spectrometry platforms over multiple years
Surface proteins are one of the most important and common matrices for clinical chemistry and proteomic analyses. With the rapid developments in mass spectrometry (MS)-based proteomics methods, label-free quantitative proteomics has become an increasingly popular tool for profiling global protein ab...
ORGANISM(S): Homo sapiens (Human) 
2021-12-30 | PXD022721 | Pride
Quantitative proteomics Reproducibility Label-free quantification Mass spectrometry Surfaceome Large-scale 
ProteomicsDeep profiling and custom databases improve detection of proteoforms generated by alternative splicing
Alternative pre-mRNA splicing has long been proposed to greatly contribute to proteome complexity. However, the extent to which mature mRNA isoforms are successfully translated into protein remains controversial. Here, we used high-throughput RNA sequencing and mass spectrometry (MS)-based proteomic...
ORGANISM(S): Homo sapiens (Human) 
2019-10-14 | PXD012556 | Pride
Human Proteoforms Alternative splicing Nanolc-ms/ms Proteome Jurkat t cells Rna-seq 
ProteomicsProteomic profiling of Labeo Rohita; a widely cultivated fish
The aim of this study was to develop a Peptide Atlas repository for Labeo rohita. Using LC-MS/MS, we have performed in-depth proteomics analysis of 19 different sample types, including 17 tissue samples, plasma from female fish and embryo 4-day post fertilization. Whole analysis resulted in the iden...
ORGANISM(S): Labeo rohita (Indian major carp) 
2022-01-10 | PXD026377 | Pride
Orbitrap fusion Labeo rohita Rohu peptideatlas 
ProteomicsProteomic profiling of embryonic retina to facilitate ocular disease gene discovery
To expedite gene discovery in eye development and its associated defects, we previously developed a bioinformatics resource-tool iSyTE (integrated Systems Tool for Eye gene discovery). However, iSyTE is presently limited to lens tissue and is predominantly based on transcriptomics datasets. Therefor...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-09 | PXD039490 | Pride
Gene discovery Proteome Embryogenesis Retina Mass spectrometry Isyte Development 
Sort   by:  
 Page size