Sort   by:  
 Page size 
ProteomicsDiethylation
In this study we compared diethylation using acetaldehyde-13C2/13C1 and acetaldehyde-2H4/1H4. Light and heavy labeled samples were combined in a ratio of 1:1 and analyzed on a LC-MSMS system using an OrbitrapXL. We analyzed ten techical replicates of each labeling version (13C/12C and 2H/1H) and com...
ORGANISM(S): Homo sapiens (Human) 
2022-03-02 | PXD001256 | Pride
Diethylation Retention time shift Stable isotope labeling Reductive amination Orbitrapxl 
ProteomicsN‑Glycoproteomics Study of Putative N‑Glycoprotein Biomarkers of Drug Resistance in MCF‑7/ADR Cells
Currently, drug resistance of anti-cancer therapy has become the main cause of low survival rate and poor prognosis. Full understanding of drug resistance mechanisms is an urgent request for further development of anti-cancer therapy and improvement of prognosis. Here we present our N-glycoproteomi...
ORGANISM(S): Homo sapiens (Human) 
2023-12-30 | PXD036101 | Pride
Mcf-7/adr cells · mcf-7 cells · drug resistance · diferential n-glycosylation · n-glycoproteomics 
ProteomicsHuman Breast LC-MSMS - Quantitative site- and structure-specific N-glycoproteomics characterization of differential N-glycosylation in MCF-7/ADR cancer stem cells
Cancer stem cells (CSCs) are reported to be responsible for tumor initiation, progression, metastasis, and therapy resistance where P-glycoprotein (P-gp) as well as other glycoproteins are involved. Identification of these glycoprotein markers is critical for understanding the resistance mechanism a...
ORGANISM(S): Homo sapiens (Human) 
2020-02-21 | PXD013836 | Pride
Human Breast Lc-msms Cscs Mcf7/adr 
UnknownMetabolic patterns of new psychoactive substances: Methyl-ketamine and 2-oxo-PCE in rats using UHPLC-QTOF analysis.
Not available
S-EPMC12281064 | biostudies-literature
UnknownN-Glycoproteomics Study of Putative N-Glycoprotein Biomarkers of Drug Resistance in MCF-7/ADR Cells.
Not available
S-EPMC9590513 | biostudies-literature
ProteomicsPutative N-glycoprotein markers of MCF-7/ADR cancer stem cells from N-glycoproteomics characterization of the whole cell lysate
Being the most malignant disease among females, breast cancer has morbidity and mortality in the first and second positions among various cancers [1]. Up to now, chemotherapy has been the most common therapy [2]; however, multidrug resistance (MDR) often occurs to give low overall survival rate. Thu...
ORGANISM(S): Homo sapiens (Human) 
2023-07-04 | PXD036095 | Pride
Mcf-7/adr cscsmcf-7 cscsdrug resistancedifferential n-glycosylationn-glycoproteomics 
ProteomicsVersatile roles of Annexin A4 in ccRCC: impact on membrane repair, transcriptional signatures and composition of the tumor microenvironment
Clear cell renal cell carcinoma (ccRCC) is the most prevalent type of renal malignant disease and is characterized by dismal prognosis in the metastasized setting. Invasive growth of cancer cells relates to high levels of compressive forces translating to relevant damage of the plasma membrane. Howe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-05-21 | MSV000094814 | MassIVE
ProteomicsJMod: Joint modeling of mass spectra for empowering multiplexed DIA proteomics
The throughput of mass spectrometry (MS) proteomics can be increased substantially by multiplexing that enables parallelization of data acquisition. Such parallelization in the mass domain (plexDIA) and the time domain (timePlex) increases the density of mass spectra and the overlap between ions or...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Saccharomyces Cerevisiae (ncbitaxon:4932) 
2025-05-21 | MSV000097957 | MassIVE
MetabolomicsGNPS-
GNPS-
ORGANISM(S): Camellia Sinensis (ncbitaxon:4442) Camellia Sinensis Var. Sinensis (ncbitaxon:542762) 
2019-03-18 | MSV000083595 | GNPS
ProteomicsMaximally-multiplexed proteome quantification platform for isotopic metabolic and chemical labeling
Quantitative proteomic platforms based on precursor intensity in mass spectrometry (MS1-level) uniquely support in vivo metabolic labeling with superior quantification accuracy but suffers from limited multiplexity (≤3-plex) and frequent missing quantities. Herein, we present a maximally-multiplexed...
ORGANISM(S): Homo sapiens (Human) 
2020-03-19 | PXD009952 | Pride
Diethylation Heat shock Silac-6plex Protein quantification Hela cell Quantification Silac De-6plex Heat shock response 
Sort   by:  
 Page size