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Quantitative metaproteomics is a relatively new research field by applying proteomics technique to study microbial proteins of microbiome, and holds the great potential to truly quantify the functional proteins actually expressed by microbes in the biological environment such as gastrointestinal tra...
ORGANISM(S): Mus musculus (Mouse) 
2018-12-17 | PXD011735 | Pride
Stool samples were collected from 4 children and subjected to deep gut metaproteomics analysis for in-depth understanding the functional compositions of human gut mcirobiome.
ORGANISM(S): human gut metagenome 
2017-08-10 | PXD005619 | Pride
Mucosal-luminal interface (MLI) samples were collected from a cohort of children with new-onset IBD and microbial cells were harvested and processed for metaproteomic analysis. Deep metaproteomics data analysis was then performed for better understanding the MLI microbiota functions in the developme...
ORGANISM(S): human gut metagenome 
2018-08-03 | PXD007819 | Pride
The gut microbiome's pivotal role in health and disease is well-established. SARS-CoV-2 infection often causes gastrointestinal symptoms and is associated with changes of the microbiome in both human and animal studies. While hamsters serve as important animal models for coronavirus research, there ...
ORGANISM(S): Mesocricetus auratus (Golden hamster) 
2025-05-13 | PXD057158 | Pride
A differential lysis approach was developed with different strength of lysis buffers (urea and/or sodium dodecyl sulfate) and applied on human stool samples to separate different microbial species to increase the depth of metaproteomic measurements. We showed that the lysates dominating by proteins ...
ORGANISM(S): Escherichia coli 
2023-03-27 | PXD016787 | Pride
Extensive ground truth dataset for the assessment of differential expression analyses in metaproteomics
We developed a free-flow isoelectric focusing (FFIEF) based metaproteomics workflow to reduce the host interferences and enrich the low-abundant bacteria for better interpretation of salivary microbiome. We firstly tested the pretreatment module that could significantly reduce the host interferences...
ORGANISM(S): human saliva metagenome 
2022-11-17 | PXD026727 | Pride
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