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ProteomicsIsobaric Labeling Quantitative Metaproteomics for the Study of Gut Microbiome Response to Arsenic
Quantitative metaproteomics is a relatively new research field by applying proteomics technique to study microbial proteins of microbiome, and holds the great potential to truly quantify the functional proteins actually expressed by microbes in the biological environment such as gastrointestinal tra...
ORGANISM(S): Mus musculus (Mouse) 
2018-12-17 | PXD011735 | Pride
Isobaric labeling Metapro-iq Metaproteomics Gut microbiome Arsenic Tandem mass tags Label free 
ProteomicsMetaNovo : an open-source pipeline for probabilistic peptide discovery in complex metaproteomic datasets
Results We compared MetaNovo to published results from the MetaPro-IQ pipeline on 8 human mucosal-luminal interface samples, with comparable numbers of peptide and protein identifications, many shared peptide sequences and a similar bacterial taxonomic distribution compared to that found using a ma...
ORGANISM(S): human gut metagenome 
2023-05-16 | PXD030708 | Pride
Metaproteomics De novo sequencing Probabilistic 
ProteomicsMouse gut metaproteome - MetaPro-IQ: a universal metaproteomic approach to studying human and mouse gut microbiota
The mouse stool samples were collected from different diets fed mice and bacterial cells were harvest for metaproteomic analysis for understanding the role ofdiet on gut microbiota.
ORGANISM(S): mouse gut metagenome 
2016-07-05 | PXD003527 | Pride
Mouse Gut microbiota Metaproteomics Lc-ms/ms 
ProteomicsHuman MLI metaproteome - MetaPro-IQ: a universal metaproteomic approach to studying human and mouse gut microbiota
Human mucosal-luminal interface (MLI) samples were collected from 8 different children and bacterial cells were harvest for metaproteomic analysis for understanding the MLI microbiota functions.
ORGANISM(S): human gut metagenome 
2016-07-05 | PXD003528 | Pride
Gut microbiota Human Metaproteomics Lc-ms/ms 
ProteomicsEvaluating the protein extraction methods for gut metaproteomics
Human stool samples were collected, microbial cells were harvested and subjected to protein extraction using different protocols for metaproteomics analyses. The protein extraction methods differ from the usage of different lysis buffer (SDS, urea and commercially available B-Per reagent), bead beat...
ORGANISM(S): human gut metagenome 
2017-07-17 | PXD005969 | Pride
Protein extraction Metaproteomics Microbiome Bead beating Ultrasonication 
ProteomicsHuman gut microbiome cultured over time responsed differently to drug stimulation
In vitro gut microbiota models are often used to study drug-microbiome interaction. Similar to culturing individual microbial strains, the biomass accumulation of in vitro gut microbiota follows a logistic growth curve. Current studies on in vitro gut microbiome responses introduce drug stimulation ...
ORGANISM(S): gut metagenome 
2022-03-01 | PXD017390 | Pride
Drug Microbiome Metaproteomics 
ProteomicsEvaluating in vitro culture medium of mouse gut microbiome
The mice stool samples were collected for culturing with different medium for understanding the role of different medium component on the microbiome.
ORGANISM(S): mouse gut metagenome 
2018-06-15 | PXD006808 | Pride
Medium In vitro Gut microbiome Culture 
ProteomicsExtracellular vesicles isolated from the descending colon of pediatric patients with inflammatory bowel disease and control patients
Characterizing the proteomic profile of extracellular vesicles isolated from the descending colon of pediatric patients with inflammatory bowel disease and control participants
ORGANISM(S): Homo sapiens (Human) 
2018-09-11 | PXD007959 | Pride
Extracellular vesicles Inflammatory bowel disease Colon 
ProteomicsPediatric IBD MLI metaproteomics
Mucosal-luminal interface (MLI) samples were collected from a cohort of children with new-onset IBD and microbial cells were harvested and processed for metaproteomic analysis. Deep metaproteomics data analysis was then performed for better understanding the MLI microbiota functions in the developme...
ORGANISM(S): human gut metagenome 
2018-08-03 | PXD007819 | Pride
Lc-msms Intestine Microbiome Ibd Children 
ProteomicsHunam gut microbiome metaproteomcis in LP1
The samples of gut micorbiota were collected in "Lunar Palace 365" experiment. The "Lunar Palace 365" experiment was a 370-day, multicrew, closed experiment carried out in a ground-based experimental BLSS platform named Lunar Palace 1. Deep metaproteomics data analysis was then performed for better ...
ORGANISM(S): human gut metagenome 
2023-05-10 | PXD027661 | Pride
Mood Lp1 Human gut microbiome 
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