Sort   by:  
 Page size 
ProteomicsMycobacterium tuberculosis ATP-binding Proteome
Mtb was grown as either an actively growing normal culture or as a hypoxia-induced dormant culture. Whole cell lysates of live bacteria were obtained by mechanical disruption with silica beads. ATP-binding proteins were covalently labeled with desthiobiotin-tagged ATP (ActivX, Thermo Pierce). This c...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2013-04-08 | PXD000141 | Pride
Abpp Atp M. tuberculosis Lc-ms/ms 
ProteomicsMTB_ATP-bindingProteome
Mycobacterium tuberculosis ATP-binding Proteome
ORGANISM(S): Mycobacterium Tuberculosis 
2013-12-31 | PAe004062 | PeptideAtlas
ProteomicsEstablishment of Minimum Protein Standards for Mycobacterium tuberculosis-Derived Extracellular Vesicles through Comparison of EV Enrichment Methods
Extracellular vesicles (EVs) produced by Mycobacterium tuberculosis, the causative agent of tuberculosis, are involved in acquiring nutrients, evading host immune mechanisms, and modulating the host immune response. The functions of these M. tuberculosis EVs (MEVs)are hypothesized to be due to the d...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2025-05-07 | PXD056465 | Pride
Proteomics Mycobacterium tuberculosis Liquid chromatography-mass spectrometry/mass spectrometry Extracellular vesicles Bruker timstof pro 
ProteomicsProteomics of Mycobacterium tuberculosis Beijing genotype after acquisition of Isoniazid resistance
This project provides the first characterization of protein differences in clinical isolates of Mtb after acquisition of resistance to isoniazid (INH), one of the most important drug treatment options against TB. This study determines the global protein differences in a clinical isogenic pair of Mtb...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2016-03-14 | PXD002986 | Pride
Isoniazid Tuberculosis Resistance Ltq Proteomics Mycobacterium Beijing Lc-ms/ms 
ProteomicsChanges in the Membrane-Associated Proteins of Exosomes Released from Human Macrophages after Mycobacterium tuberculosis Infection - Biotinylated
Tuberculosis (TB) is the deadliest infectious disease worldwide. One obstacle hindering the elimination of TB is our lack of understanding of host-pathogen interactions. Exosomes, naturally loaded with microbial molecules, are circulating markers of TB. Changes in the host protein composition of exo...
ORGANISM(S): Homo sapiens (Human) 
2018-08-06 | PXD010659 | Pride
Biotin Asp-n 
ProteomicsChanges in the membrane proteome of exosomes released from human macrophages after infection with Mycobacterium tuberculosis.
One of the greatest obstacles to eliminating TB is the lack of predictive and diagnostic biomarkers. Exosomes are a promising alternative source of biomarkers for TB since they can carry mycobacterial antigens. We hypothesize that exosomes from Mtb-infected macrophages exhibit a characteristic selec...
ORGANISM(S): Homo sapiens (Human) 
2016-12-20 | PXD004062 | Pride
Mycobacterium tuberculosis  exosomes  membrane proteins  macrophage 
ProteomicsComprehensive biochemical characterization of Mycobacterium tuberculosis clonal strains after isoniazid resistance
This project describes the isoniazid (INH) resistance acquisition event in Mycobacterium tuberculosis (Mtb) from the proteomics perspective. In this way, an exploration of the protein differences, comparing clonal INH susceptible (INHs) and INHr pairs of Mtb were evaluated. One clonal clinical and o...
ORGANISM(S): Mycobacterium tuberculosis 
2018-06-25 | PXD009549 | Pride
Mycobacterium tuberculosis Isoniazid resistance 
ProteomicsCo-immunoprecipitation and proteomic analysis of Major Histocompatibility Complex Class I-related (MR1) mutants
Identification of cellular proteins mediating presentation of bacterial antigens by the MHC I-related protein MR1. MR1 mutant proteins that differ in their capacity to present antigens from different sources were immunoprecipitated and their interacting proteins were compared to identify candidate p...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD062277 | Pride
Co-immunoprecipitation Antigen presentation Mr1 Endosomal trafficking 
ProteomicsProtein profile at different cellular fractions of Mycobacterium tuberculosis strains after exposure to Isoniazid
Out of the 10 million of tuberculosis (TB) cases estimated in the world, around 14% are isoniazid (INH) resistant among new cases and 29% among previously treated cases in the last decade. INH is one of the oldest but also one of the more potent drugs to eliminate Mycobacterium tuberculosis (Mtb), t...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2019-06-17 | PXD007588 | Pride
Cellular fractions Tuberculosis Isoniazid Shotgun proteomics Lc-ms/ms 
ProteomicsLongitudinal Proteomic Profiling of Bronchoalveolar Lavage Fluid (BALF) and Serum in Tuberculosis Patients
The scope of this project is to investigate dynamic and persistent proteomic changes in tuberculosis (TB) patients during the course of treatment by analyzing paired bronchial alveolar lavage fluid (BALf) and serum samples collected at diagnosis and after 25 weeks of therapy. By comparing patient sa...
ORGANISM(S): Mycobacterium tuberculosis H37Rv Homo sapiens (Human) 
2026-03-17 | PXD073337 | Pride
Sort   by:  
 Page size