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The mechanisms by which the mouse pathogen Citrobacter rodentium triggers effacement of the brush border microvilli, colitis, hyperplasia and dysbiosis remain poorly understood. We investigated the impact of C. rodentium infection on the proteomic and metabolic landscapes of intestinal epithelial ce...
ORGANISM(S): Citrobacter rodentium Mus musculus (Mouse) 
2018-01-10 | PXD005004 | Pride
Whole genome trancription study of Citrobacter rodentium grown in rich media.
ORGANISM(S): Citrobacter rodentium 
We used human embryonic kidney HEK293T cells transfected with human GPR35 cDNAs as baits that were engineered to express Strep or hemagglutinin (HA) tags at the C terminus to perform an unbiased proteomics survey for GPR35 interaction partners.
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD011269 | Pride
Harmful algal blooms are induced largely by nutrient enrichment common in warm waters. An increasingly frequent phenomenon is the “red tide”: blooms of dinoflagellate microalgae that accumulate toxins lethal to other organisms in high doses. Here, we present the de novo assembled genome (~4.75 Gbp) ...
ORGANISM(S): Prorocentrum cordatum 
2023-10-18 | PXD046193 | Pride
Chlamydia trachomatis remains a leading cause of bacterial sexually transmitted infections and preventable blindness worldwide. There are, however, limited in vitro models to study the role of host genetics in the response of macrophages to this obligate human pathogen. Here, we describe an approach...
ORGANISM(S): Chlamydia trachomatis Homo sapiens (Human) 
2018-02-14 | PXD005858 | Pride
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