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MetabolomicsJiawei Shoutai Pill Promotes Embryo Implantation via PPAR Signaling and Endometrial Microbiota Remodeling: An Integrative Multi-Omics Study
Background: Recurrent implantation failure (RIF) remains a major barrier to successful assisted reproductive technology, given the lack of effective, mechanism-informed interventions to enhance endometrial receptivity. Jiawei Shoutai Wan (pills) (JWSTW), a modified formulation of the classic Shoutai...
2026-03-31 | MTBLS14199 | MetaboLights
ProteomicsChanges in proteomics of endometrial tissue during secretion of polycystic ovary syndrome may affect endometrial receptivity
Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies among fertile women. PCOS patients have been confirmed to be accompanied by an increased risk of pregnancy complication, and the exact cause is still unclear. Many factors may cause this situation, and impaired endometrial r...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD024735 | Pride
Endometrium Proteomics. Endometrial receptivity Pcos 
ProteomicsComparative endometrial proteomics among fertile women, intrauterine device carriers, and recurrent implantation failure patients using iTRAQ methodology
Endometrial receptivity is imperative to achieving pregnancy in humans. A disruption in the development of endometrial receptivity is responsible for recurrent implantation failures (RIF) of endometrial origin. To further understand the molecular mechanisms behind the endometrial receptivity process...
ORGANISM(S): Homo sapiens (Human) 
2019-11-06 | PXD011094 | Pride
Intrauterine device (iud) Isobaric tags for relative and absolute quantification (itraq) Recurrent implantation failure (rif) Endometrial receptivity Endometrium 
ProteomicsGPX3 improves endometrial receptivity by inhibiting ferroptosis via Nrf2/GPX4 pathway in sows
Obesity is a vital inducement of reproductive disorders during early pregnancy in mammal. However, the effect and molecular mechanism of attenuating endometrial receptivity under obesity remain largely unknown. Here, we identified that GPX3 as a potential target for improving endometrial receptivity...
ORGANISM(S): Sus Scrofa Domesticus 
2025-07-22 | PXD066372 |
TranscriptomicsGenome-wide identification of micro-ribonucleic acids associated with human endometrial receptivity in natural and stimulated cycles by deep sequencing
In this study, we took advantage of deep sequencing approaches to investigate the miRNA expression profiles of human endometrium on days LH+2 and LH+7 in natural cycles, and compare them with those on days hCG+4 and hCG+7 in stimulated cycles during IVF treatment. Examination of miRNA expression in ...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-26516 | biostudies-arrayexpress
GenomicsBiological significance of CDYL in endometrial receptivity
Biological significance of CDYL in endometrial receptivity
PRJNA592906 | ENA
GenomicsUnveiling the Molecular Mechanisms of ligustilide in Enhancing Endometrial Receptivity
Unveiling the Molecular Mechanisms of ligustilide in Enhancing Endometrial Receptivity
PRJNA1283207 | ENA
ProteomicsMyosin Heavy Chain 10 dysregulation in infertile endometrial epithelial cells impairs adhesive capacity
Endometrial receptivity is defined as the functional, morphological, and molecular changes of the endometrium occurring during a limited time period in the menstrual cycle called the ‘window of implantation’. The endometrial luminal epithelial cells are critical in producing this receptivity as thei...
ORGANISM(S): Homo sapiens (Human) 
2026-05-05 | PXD062326 | Pride
Endometrial receptivity Epithelium Endometrial Cell adhesion Actin cytoskeleton Infertility Myh10 Myosin 2 Embryo implantation failure 
GenomicsMicroRNA markers of human endometrial receptivity
MicroRNA markers of human endometrial receptivity
PRJNA429485 | ENA
ProteomicsThe effect of obesity on uterine receptivity is mediated by endometrial extracellular vesicles that control human endometrial stromal cell decidualization and trophoblast invasion
The objectives of the present study were to determine whether obesity impacts human decidualization and the endometrial control of trophoblast invasion (both of which are required for embryo implantation) and evaluate the potential involvement of endometrial extracellular vesicles (EVs) in the regul...
ORGANISM(S): Homo sapiens (Human) 
2023-10-09 | PXD039568 | Pride
Vesicules Human Decidualization Proteomic 
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