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UnknownOutcomes of children with BCR-ABL1–like acute lymphoblastic leukemia treated with risk-directed therapy based on the levels of minimal residual disease.
Not available
S-EPMC4162497 | biostudies-literature
ProteomicsMolecular basis for differential activation of p101 and p84 complexes of PI3Kg by Ras and GPCRs
Using hydrogen deuterium exchange mass spectrometry, we reveal molecular differences between the two p110g-p84 and p110g-p101 complexes that explain their differential activation.
ORGANISM(S): Homo sapiens (Human) 
2023-03-09 | PXD035723 | Pride
Pi3kg P101 Ras P110g Hdx-ms Hdx Gby 
ProteomicsUsing HDX-MS to study Rab and Ral covalently bound to MRTX1257
Here we use HDX to study covalently modified Rab1a and RalA in both their apo states and bound to MRTX1257 to see how this compound affects the overall secondary structure of the proteins.
ORGANISM(S): Homo sapiens (Human) 
2025-03-10 | PXD041440 | Pride
Rab Hdx-ms Ral Hdx Gtpase 
ProteomicsDetailing the Structural and Dynamic Interactions Between WDR44 and Rab11
DR44 is a Rab11 effector protein that is thought to regulate ciliogenesis by competing with pro-ciliogenesis factors for Rab11 binding. The structure of WDR44 and the molecular mechanism of its interaction with Rab11 is unknown. To explore the interactions between these two proteins multiple WDR44 c...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD035741 | Pride
Hdx-ms Wdr44 Rab11 
ProteomicsDetailing the Structural and Dynamic Interactions Between WDR44 and Rab11
Analysis of the interactions between WDR44 and Rab11 utilizing HDX-MS
ORGANISM(S): Homo sapiens (Human) 
2023-02-22 | PXD032837 | Pride
Hdx-ms Wdr44 Rab11 
ProteomicsApolipoprotein A-II Increases Cholesterol Efflux Capacity of Mature High-Density Lipoproteins Via the Apolipoprotein A-I C-terminus
Samples were processed using Global and Limited Proteolysis (LiP). Peptides and proteins were identified using MaxQuant (v1.6.17.0), then summarized using R package RomicsProcessor.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-07-29 | MSV000095479 | MassIVE
UnknownMethotrexate-induced neurotoxicity and leukoencephalopathy in childhood acute lymphoblastic leukemia.
Not available
S-EPMC3948096 | biostudies-literature
UnknownSubcortical Brain Development in Autism and Fragile X Syndrome: Evidence for Dynamic, Age- and Disorder-Specific Trajectories in Infancy.
Not available
S-EPMC9762548 | biostudies-literature
UnknownThe impact of viral mutations on recognition by SARS-CoV-2 specific T cells.
Not available
S-EPMC8552693 | biostudies-literature
UnknownCollagen Prolyl Hydroxylases Are Bifunctional Growth Regulators in Melanoma.
Not available
S-EPMC7015666 | biostudies-literature
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