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GenomicsCounteraction of myocardial ferritin heavy chain deficiency by heme oxygenase-1
Counteraction of myocardial ferritin heavy chain deficiency by heme oxygenase-1
PRJNA856316 | ENA
TranscriptomicsCounteraction of myocardial ferritin heavy chain deficiency by heme oxygenase-1
To investigate the functional significance of myocardial ferritin heavy chain (FtH) in a model of acute myocardial infarction (MI). FtH was deleted using FtH floxed mice and Sm-22 Cre mice on a C57/bl6 background At 3 hours following 45 minutes of ischemia induced via ligation of left ant. decsendin...
ORGANISM(S): Mus musculus 
2022-07-11 | GSE207609 | GEO
MetabolomicsFatal COVID-19 pulmonary disease involves ferroptosis.

SARS-CoV-2 infection causes severe pulmonary manifestations, with poorly understood mechanisms and limited treatment options. Hyperferritinemia and disrupted lung iron homeostasis in COVID-19 patients imply that ferroptosis, an iron-dependent cell death, may occur. Immunostaining and lipidomic an...

2024-07-11 | MTBLS3107 | MetaboLights
UnknownOligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain.
Not available
S-EPMC7116799 | biostudies-literature
UnknownFerritin heavy chain protects the developing wing from reactive oxygen species and ferroptosis.
Not available
S-EPMC6786644 | biostudies-literature
UnknownMolecular Characterization and Functional Analysis of a Ferritin Heavy Chain Subunit from the Eri-Silkworm, Samia cynthia ricini.
Not available
S-EPMC5666808 | biostudies-literature
ProteomicsFerritin-mediated iron detoxification mediates hypothermia survival in Caenorhabditis elegans and murine neurons.
How animals rewire cellular programs to survive cold is a fascinating problem with potential biomedical implications, ranging from emergency medicine to space travel. Studying a hibernation-like response in the free-living nematode Caenorhabditis elegans, we uncovered a regulatory axis that enhances...
ORGANISM(S): Caenorhabditis elegans 
2022-10-14 | PXD034794 | Pride
Ferritin heavy chain Ferrous iron Foxo Ets-4 Neuroprotection Ferroxidase Daf-16 Fth1 Cold Ftn-1 Pqm-1 Ros Antioxidant Hibernation Iron Fe2+ Hypothermia 
UnknownMagnetic resonance imaging focused on the ferritin heavy chain 1 reporter gene detects neuronal differentiation in stem cells.
Not available
S-EPMC10075097 | biostudies-literature
UnknownHeterozygous Nonsense Variants in the Ferritin Heavy Chain Gene FTH1 Cause a Neuroferritinopathy.
Not available
S-EPMC10510067 | biostudies-literature
UnknownStructural Insights for the Stronger Ability of Shrimp Ferritin to Coordinate with Heavy Metal Ions as Compared to Human H-Chain Ferritin.
Not available
S-EPMC8346123 | biostudies-literature
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