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ProteomicsProteomic profiling of RNase III-dependent asRNA regulation in E. coli
In an effort to determine if the RNase III-dependent asRNA regulation had an effect on protein production in E. coli we conducted two TMT 6-plex experiments comparing cultures of wildtype E. coli, rnc-14, rnc-38, hfq in the stationary and exponential phase.
ORGANISM(S): Escherichia coli 
2020-06-18 | PXD011180 | Pride
E. coli Antisense rnas Rnase iii 
ProteomicsConfirmation of SOMAmer® Enrichment from Biological Matrices using Mass Spectrometry, cell part 2
In an effort to confirm binding of SOMAmer®s to their respective targets in an endogenous matrix, we have conducted a series of experiments using SOMAmer®s to enrich target proteins followed by measurement using two mass spectrometry techniques: data dependent analysis (DDA) and multiple reaction m...
ORGANISM(S): Homo sapiens (Human) 
2018-08-03 | PXD008820 | Pride
Cell lysate Blood plasma Blood serum Conditioned media Aptamer Somamer 
ProteomicsConfirmation of SOMAmer® Enrichment from Biological Matrices using Mass Spectrometry, serum
In an effort to confirm binding of SOMAmer®s to their respective targets in an endogenous matrix, we have conducted a series of experiments using SOMAmer®s to enrich target proteins followed by measurement using two mass spectrometry techniques: data dependent analysis (DDA) and multiple reaction m...
ORGANISM(S): Homo sapiens (Human) 
2018-08-03 | PXD008822 | Pride
Cell lysate Blood plasma Blood serum Conditioned media Aptamer Somamer 
ProteomicsConfirmation of SOMAmer® Enrichment from Biological Matrices using Mass Spectrometry
In an effort to confirm binding of SOMAmer®s to their respective targets in an endogenous matrix, we have conducted a series of experiments using SOMAmer®s to enrich target proteins followed by measurement using two mass spectrometry techniques: data dependent analysis (DDA) and multiple reaction m...
ORGANISM(S): Homo sapiens (Human) 
2018-08-03 | PXD008819 | Pride
Cell lysate Blood plasma Blood serum Conditioned media Aptamer Somamer 
ProteomicsConfirmation of SOMAmer® Enrichment from Biological Matrices using Mass Spectrometry, plasma
In an effort to confirm binding of SOMAmer®s to their respective targets in an endogenous matrix, we have conducted a series of experiments using SOMAmer®s to enrich target proteins followed by measurement using two mass spectrometry techniques: data dependent analysis (DDA) and multiple reaction m...
ORGANISM(S): Homo sapiens (Human) 
2018-08-03 | PXD008821 | Pride
Cell lysate Blood plasma Blood serum Conditioned media Aptamer Somamer 
ProteomicsConfirmation of SOMAmer® Enrichment from Biological Matrices using Mass Spectrometry, urine
In an effort to confirm binding of SOMAmer®s to their respective targets in an endogenous matrix, we have conducted a series of experiments using SOMAmer®s to enrich target proteins followed by measurement using two mass spectrometry techniques: data dependent analysis (DDA) and multiple reaction m...
ORGANISM(S): Homo sapiens (Human) 
2018-08-03 | PXD008823 | Pride
Cell lysate Blood plasma Blood serum Conditioned media Aptamer Somamer 
ProteomicsTarget identification for 11q13 amplicon
Proteomic strategy to define therapeutically relevant targets in cell lines that contain the 11q13 amplicon compared to those that do not and to ascertain which genes are amplified at the protein level and, concomitantly, are key drivers for tumor growth and/or maintenance. Furthermore, so called p...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000080001 | MassIVE
ProteomicsTarget identification for 11q13 amplicon
Proteomic strategy to define therapeutically relevant targets in cell lines that contain the 11q13 amplicon compared to those that do not and to ascertain which genes are amplified at the protein level and, concomitantly, are key drivers for tumor growth and/or maintenance. Furthermore, so called p...
ORGANISM(S): Homo sapiens (Human) 
2015-08-04 | PXD002486 | Pride
Human Lc-msms Head and neck Cell surface protein enrichment Breast 11q13 Liver Oscc Tmt6 quantitation 
ProteomicsConfirmation of SOMAmer® Specificity in Serum using Mass Spectrometry
Experiments were conducted to confirm SOMAmer® reagent specificity by enrichment in serum from elderly subjects (>65 years, male n=1 and female n=1, purchased from commercial vendor) followed by measurement using data dependent analysis (DDA). Non-specific binding was assessed in the biological matr...
ORGANISM(S): Homo sapiens (Human) 
2024-08-22 | PXD054671 | Pride
Lc-msms Human serum Aptamer 
OtherQuantitative Proteomic Verification of Membrane Proteins as Potential Therapeutic Targets Located in the 11q13 Amplicon in Cancers.
Data from ProteomeXchange, PXD ID: PXD002486. Experiment: 11q13_group3_HHn1, file: folder summary. Published as part of J Proteome Res. 2015 Jul 29 . From the Abstract: {{i}} ... We employed a tandem mass spectrometry proteomics approach using tumor cell lines to identify the cell surface proteins ...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320017500 | GPMDB
Resource Reanalysis 
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