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MetabolomicsMultiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level (Metabolite profiling)

Medulloblastomas (MBs) are malignant pediatric brain tumors that are molecularly and clinically very heterogenous. The application of omics technologies - mainly studying nucleic acids - has significantly improved MB classification and stratification, but treatment options are still unsatisfactor...

2024-05-30 | MTBLS9830 | MetaboLights
ProteomicsProfiling antibody responses to M. tuberculosis proteins in TB suspects’ sera using full-proteome microarrays.
Understanding the immune response to tuberculosis requires greater knowledge of humoral responses. To characterize antibody targets and the effect of disease parameters on target recognition, we developed a systems immunology approach that integrated detection of antibodies against the entire Mycob...
ORGANISM(S): Homo sapiens 
2010-07-13 | E-GEOD-19433 | biostudies-arrayexpress
ProteomicsUnderstanding early AutoAb signatures in Pituitary Adenomas using CDI HuProt™ (Human Proteome Microarray)
CDI HuProt™ (Human Proteome Microarray), was used to study Pituitary Adenomas PAs (Acromegaly, Cushing's and NFPA) using serum samples, from around 14 individuals (4 Healthy control, 4 Acromegaly, 3 Cushing’s and 3 NFPAs patient samples) were used study their autoantibody profiles. Patient serum sam...
ORGANISM(S): Homo sapiens 
2022-09-30 | E-MTAB-11947 | biostudies-arrayexpress
ProteomicsReanalysis of Pandey lab's draft of the human proteome
The availability of human genome sequence has transformed biomedical research over the past decade. However, an equivalent map for the human proteome with direct measurements of proteins and peptides was lacking. To this end, Akhilesh Pandey's lab reported a draft map of the human proteome based on...
ORGANISM(S): Homo sapiens 
2015-03-10 | E-PROT-1 | biostudies-arrayexpress
ProteomicsNUDT2 Knockout full proteome mouse
Proteome comparison between bone-marrow cells isolated from wildtype and NUDT2 knockout mice.
ORGANISM(S): Mus musculus (Mouse) 
2021-11-03 | PXD023219 | Pride
Mouse Full proteome Lc-ms Nudix hydolases Bone-marrow 
ProteomicsRescuing discarded spectra: Full comprehensive analysis of a minimal proteome.
A common problem encountered when performing large-scale mass spectrometry proteome analysis is the loss of information due to the high percentage of unassigned spectra. To determine the causes behind this loss we have analyzed the proteome of one of the smallest living bacteria that can be grown ax...
ORGANISM(S): Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
2016-01-05 | PXD002779 | Pride
Translation errors : mass spectroscopy Post-translational modifications (ptms) Protein identification Proteome coverage Unassigned spectra 
UnknowniProX: an integrated proteome resource.
Not available
S-EPMC6323926 | biostudies-literature
ProteomicsProfiling antibody responses to M. tuberculosis proteins in TB suspects’ sera using full-proteome microarrays.
Understanding the immune response to tuberculosis requires greater knowledge of humoral responses. To characterize antibody targets and the effect of disease parameters on target recognition, we developed a systems immunology approach that integrated detection of antibodies against the entire Mycoba...
ORGANISM(S): Mycobacterium tuberculosis H37Rv Homo sapiens 
2010-07-14 | GSE19433 | GEO
ProteomicsProteome validation for novel full-length genes in the giant panda
we applied RNA-seq to detect novel expressed transcripts in 12 tissues of giant pandas, using a transcriptome reconstruction strategy combining reference-based and de novo methods. Then we used mass spectrometry method to identify proteomes of five selected tissues, aiming at validating these novel...
ORGANISM(S): Ailuropoda melanoleuca (Giant panda) 
2015-12-23 | PXD002917 | Pride
Testis Pituitary Brain Giant panda Tongue Lc-ltq Ovary 
UnknownMolecular weight assessment of proteins in total proteome profiles using 1D-PAGE and LC/MS/MS.
Not available
S-EPMC1182394 | biostudies-literature
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