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ProteomicsProfiling CTBP2’s genome-wide interactome in murine macrophages in resting state and during LPS-induced inflammation
We profiled the genome-wide interactome of the co-repressor C-terminal binding protein 2 (CTBP2) in primary murine macrophages (BMDM) in vehicle and LPS conditions after 3 h of stimulation. We find that CTBP2 interacts with the transcription factors NF-κB and AP-1 and forms a corepressor complex tha...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-08 | PXD063850 | Pride
Lps Macrophage Ctbp2 Inflammation Bmdm Mouse Chip-ms 
ProteomicsProfiling CTBP2’s genome-wide interactome in murine macrophages during LPS-induced inflammation – oligomerization-dependent interactions
To identify oligomerization dependent interactors of C-terminal binding protein 2 (CTBP2), we stably expressed CTBP2 wild type or a monomeric mutant (CTBP2 mono: CTBP2 C140Y, N144R, R147E, L156W) in Ctbp1-/-, Ctbp2-/- J774.1 cells and profiled their genome-wide interactome in LPS conditions after 3 ...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-08 | PXD063883 | Pride
Lps Macrophage J774.1 Ctbp2 Inflammation Oligomerization Mouse Chip-ms 
MetabolomicsNMR-based metabolic profiling of children with premature adrenarche

INTRODUCTION: Premature adrenarche (PA) for long time was considered a benign condition but later has been connected to various diseases in childhood and adulthood which remains controversial.

OBJECTIVE: To investigate the effect of premature adrenarche ...

2022-10-18 | MTBLS2387 | MetaboLights
UnknownA GATA3-specific DNAzyme attenuates sputum eosinophilia in eosinophilic COPD patients: a feasibility randomized clinical trial.
Not available
S-EPMC5883532 | biostudies-literature
UnknownAndrogen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1.
Not available
S-EPMC8364332 | biostudies-literature
UnknownTargeting mutant fibroblast growth factor receptors in cancer.
Not available
S-EPMC3809064 | biostudies-literature
ProteomicsStructure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase
Garvie CW, Wu X, Papanastasiou M, Lee S, Fuller J, Schnitzler GR, Horner SW, Baker A, Zhang T, Mullahoo JP, Westlake L, Hoyt SH, Toetzl M, Ranaghan M, de Waal L, McGaunn J, Kaplan B, Piccioni F, Yang X, Lange M, Tersteegen A, Raymond D, Lewis TA, Carr SA, Cherniack AD, Lemke C, Meyerson M, Greulich ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-06-14 | MSV000087620 | MassIVE
UnknownShared functional connectivity between the dorso-medial and dorso-ventral streams in macaques.
Not available
S-EPMC7596572 | biostudies-literature
UnknownUVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages.
Not available
S-EPMC3488256 | biostudies-literature
UnknownA comprehensive validation study of the latest version of BoneXpert on a large cohort of Caucasian children and adolescents.
Not available
S-EPMC10079872 | biostudies-literature
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