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ProteomicsHuman hair shaft LC-MS/MS - Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins
The aim of this work was to define the hair proteome after extractions with both detergent and detergent-free buffers using highly sensitive proteomics technologies based on mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2018-01-30 | PXD007224 | Pride
Human scalp hair shaft 
ProteomicsReprocessed: Chick utricle hair bundles and utricular epithelium—Orbitrap
This is a reanalysis of PXD000104. Purified hair bundles and utricular epithelium from E19-E20 chick inner ears were analyzed by LC-MS/MS to determine the abundant and enriched proteins of the hair bundle. This dataset used a Thermo Orbitrap Elite mass spectrometer for protein detection.
ORGANISM(S): Gallus gallus (Chicken) 
2015-11-17 | PXD002445 | Pride
Vestibular Hair cells Stereocilia Utricle 
UnknownUnique amino acid signatures that are evolutionarily conserved distinguish simple-type, epidermal and hair keratins.
Not available
S-EPMC3258107 | biostudies-literature
TranscriptomicsExtensive alopecia areata is reversed by IL-23 cytokine antagonism
Alopecia areata (AA) is a prevalent disease associated with major emotional distress, and lacks effective, safe therapeutics for patients with extensive hair loss. This is the first report of hair regrowth with specific cytokine antagonism, in three patients with extensive hair loss ranging from 40%...
ORGANISM(S): Homo sapiens 
2015-12-08 | E-GEOD-74761 | biostudies-arrayexpress
ProteomicsBald thigh syndrome in sighthounds
Bald thigh syndrome is a common hair loss disorder in sighthounds. The overall goal of our study was to identify the cause of bald thigh syndrome and the pathological changes associated with it. We approached this aim by comparing skin biopsies and hair shafts of affected and control dogs microscopi...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2019-11-13 | PXD012371 | Pride
Hair Greyhound dog Bald thigh syndrome Proteome 
ProteomicsA simplified sample preparation for hair and skin proteins towards the application of archaeological fur and leather
Traditional protocols for proteomics analysis usually start by extracting or solubilizing the proteins from their substrates. This step can be challenging for archaeological proteins, when they are heavily contaminated or decayed. The remains of animal fur/leather objects from the singer’s burial of...
ORGANISM(S): Bos taurus (Bovine) Ovis aries 
2023-01-17 | PXD036745 | Pride
Collagen Archaeological burial Keratin Proteomics 
UnknownRecurrent functional divergence of early tetrapod keratins in amphibian toe pads and mammalian hair.
Not available
S-EPMC3645037 | biostudies-literature
ProteomicsAutophagy controls the protein composition of hair shafts
Hair shafts are formed by terminal differentiation of hair keratinocytes (trichocytes) in which keratins and keratin-associated proteins accumulate and undergo cross-linking. Here we tested the hypothesis that maturation of the hair shaft also involves the coordinated degradation of other proteins a...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-01-17 | MSV000091072 | MassIVE
ProteomicsChick vestibular hair bundles - Molecular architecture of the chick vestibular hair bundle
Proteomic analysis of chick vestibualr hair bundles purified using the twist-off method. See Description.doc. Utricle hair bundles were purified from E20–21 chicks using the twist-off method (Gillespie & Hudspeth J Cell Biol 112, 625-640, 1991; Shin et al. Neuron 53, 371-386, 2007). NuPAGE LDS sampl...
ORGANISM(S): Gallus gallus (Chicken) 
2013-01-08 | PXD000104 | Pride
Auditory Vestibular Hair cells Stereocilia Hair bundles Utricle 
UnknownConvergent Evolution of Cysteine-Rich Keratins in Hard Skin Appendages of Terrestrial Vertebrates.
Not available
S-EPMC7086170 | biostudies-literature
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