Hartmann Kai K - OmicsDI

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pride (2)

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Mass Spectrometry (2)
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2026 (1)
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Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt am Main, Germany Frankfurt Cancer Institute, Frankfurt am Main, Germany Cardio-Pulmonary Institute, Frankfurt am Main, Germany (1)
Professor Institute of Biochemistry II Goethe University Medical Faculty University Hospital Building 75 Theodor-Stern-Kai 7 60590 Frankfurt am Main Germany (1)

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Sequencing of intraductal biopsies is feasible and potentially impacts clinical management of patients with indeterminate biliary stricture and cholangiocarcinoma.

Not available

S-EPMC5928069 | biostudies-literature

Design, Synthesis and Cellular Characterization of a Dual Inhibitor of 5-Lipoxygenase and Soluble Epoxide Hydrolase.

Not available

S-EPMC6155600 | biostudies-literature

USP28 enables oncogenic transformation of respiratory cells and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K.

Oncogenic transformation of lung epithelial cells is a multi-step process, frequently starting with the inactivation of tumor suppressors and subsequent activating mutations in proto-oncogenes, such as members of the PI3K or MAPK family. Cells undergoing transformation have to adjust to changes, suc...

ORGANISM(S): Homo sapiens (Human)

2022-04-08 | PXD032810 | Pride

Targeting Ubiquitin Signaling vulnerabilities in KEAP1-Inactivated Lung Cancer

Lung cancer cells rely on protein homeostasis regulators, especially within the ubiquitin-proteasome system (UPS), to sustain malignancy. Genetic alterations in UPS components, such as E3 ubiquitin ligases (E3s) and deubiquitinating enzymes (DUBs), are common and create context-dependent therapeutic...

ORGANISM(S): Mus musculus (Mouse)

2026-02-04 | PXD067472 | Pride

Mouse Kp Lung Kpl Kpp

USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer.

Not available

S-EPMC10307777 | biostudies-literature

Effects of medical therapies on retinopathy progression in type 2 diabetes.

Not available

S-EPMC4026164 | biostudies-literature

Protecting stable biological nomenclatural systems enables universal communication: A collective international appeal.

Not available

S-EPMC11328142 | biostudies-literature