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ProteomicsHeat ‘n Beat: A universal high-throughput end-to-end proteomics sample processing platform in under an hour
Clinical proteomics on solid tissue samples from human tumour biopsies present multiple challenges. These include limited sample availability, reducing endogenous protease activity and challenges with efficiently solubilising and digesting proteins for high throughput mass spectrometry while achievi...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2025-03-26 | PXD045405 | Pride
Sample preperation Proteomics High-throughput Heat n beat Universal Mass spec 
TranscriptomicsTranscription profiling by array of Burkholderia cenocepacia J2315 was exposed to heat stress and to stress form reactive oxygen species
B. cenocepacia J2315 was exposed to heat stress and to stress form reactive oxygen species.
To expose the cultures to heat stress, cells were grown at 37ºC to an O.D. of 0.4 to 0.45 and then transferred into a different shaking incubator at 42.5ºC, incubated for 1 hour at 150 rpm and harvested.<...
ORGANISM(S): Burkholderia cenocepacia 
2012-01-01 | E-MEXP-2791 | biostudies-arrayexpress
UnknownHeat Health Messages: A Randomized Controlled Trial of a Preventative Messages Tool in the Older Population of South Australia.
Not available
S-EPMC5615529 | biostudies-literature
TranscriptomicsSingle-cell RNA-seq of the mouse developing heart (pilot study)
The vertebrate heart is the first organ to form in the embryo and is composed of mesodermal progenitors that arise in an area termed the cardiac crescent. These give rise not only to muscle cells but also to a variety of other cell types, all of which work together to allow the heart to beat rhythmi...
ORGANISM(S): Mus musculus 
2020-01-01 | E-MTAB-7403 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli planktonic samples exposed to cis-1,2-dichloroethylene (cis-DCE)
Metabolically-engineered Escherichia coli has been used previously to degrade the ubiquitous pollutant cis-1,2-dichloroethylene (cis-DCE), and the impact of the metabolic engineering was assessed by investigating the changes in the proteome. Here, genome-wide transcriptome analysis was performed to...
ORGANISM(S): Escherichia coli 
2009-11-27 | E-GEOD-13698 | biostudies-arrayexpress
ProteomicsMass spectrometry of neuroblastoma organoids
Collect proteomic data for organoids from relapsed neuroblastoma patients
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051208 | Pride
Neuroblastoma Dia Organoids 
ProteomicsThe effect of storage time and temperature on the proteomic analysis of FFPE tissue sections
Formalin-fixed paraffin-embedded (FFPE) tissues are stable when stored at ambient temperature; they are primarily used for histopathology and immunohistochemistry (IHC). The use of FFPE tissues in molecular biological applications has increased over the years and they can be used for cancer proteomi...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2025-03-26 | PXD054596 | Pride
Proteomics Formalin-fixed paraffin-embedded (ffpe) Dia-ms Post-translational modification (ptm) Dda-ms 
MetabolomicsDecreasing peptide deformylase activity is a beneficial strategy for increasing formaldehyde resistance in Methylobacterium extorquens
Formaldehyde is a highly toxic metabolite that can cause extensive damage to DNA and proteins, and strategies to mitigate formaldehyde toxicity are poorly understood. Methylotrophic bacteria, such as Methylobacterium extorquens, thrive on one-carbon compounds as sole sources of carbon and energy. Th...
2026-10-05 | MTBLS15927 | MetaboLights
ProteomicsQuantitative comparison of deparaffinisation, rehydration and extraction methods for FFPE tissue proteomics and phosphoproteomics
Formalin-fixed paraffin-embedded tissues are suitable for proteomic and phosphoproteomic biomarker studies by data-independent acquisition mass spectrometry. The sample preparation method chosen influences the number, intensity, and reproducibility of identifications. By comparing the performance of...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-08-06 | PXD049062 | Pride
Proteomics Dia Ffpe Rat Sample preparation Phosphoproteomics 
ProteomicsMapping the Proteomic Landscape of Pancreatic Cancer: Prognostic Insights and Subtype Stratification
We conducted a comprehensive proteomic analysis on 115 PDA patient samples, with matched adjacent normal tissue and comprehensive clinical and molecular data. Differential abundance and pathway analyses identified upregulated proteins and pathways within key subgroups. Unsupervised consensus cluster...
ORGANISM(S): Homo sapiens (Human) 
2025-09-29 | PXD059074 | Pride
Survival analysis Signature Human Pancreatic Prognostic Swath-ms 
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