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TranscriptomicsDissection of the heat-shock response in Mycobacterium tuberculosis using mutants and microarrays
Regulation of the expression of heat-shock proteins plays an important role in the pathogenesis of Mycobacterium tuberculosis. The heat-shock response of bacteria involves genome-wide changes in gene expression. A combination of targeted mutagenesis and whole-genome expression profiling was used to ...
ORGANISM(S): Mycobacterium tuberculosis 
2007-03-07 | E-BUGS-2 | biostudies-arrayexpress
TranscriptomicsThermoprotection in the Drosophila hsf4 mutant
In Drosophila larvae, acquired synaptic thermotolerance following heat shock has previously been shown to correlate with the induction of heat shock proteins (Hsps) including HSP70. We tested the hypothesis that synaptic thermotolerance would be significantly diminished in a temperature-sensitive st...
ORGANISM(S): Drosophila melanogaster 
2005-11-30 | E-GEOD-2998 | biostudies-arrayexpress
TranscriptomicsDetecting Early Signs of Heat and Drought Stress in Phoenix dactylifera (Date Palm)
Phoenix dactylifera seedlings were exposed to heat, drought and combined heat & drought conditions in growth chambers. Leaf samples were collected for total RNA isolation (RNAseq, Illumina HiSeq 1000), and water soluble metabolites. The RNAseq of four biological replicates (two individuals per repli...
ORGANISM(S): Phoenix dactylifera 
2018-01-01 | E-MTAB-5756 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression studies for identifying genes imparting heat stress tolerance in wheat during grain filling.
Heat stress is one of the major abiotic stress factor that affects wheat yield. Especially, heat stress during grain filling affects grain yield besides reduced grain quality. So, in our present study, three genotypes with varied levels of tolerance to heat stress were chosen. They were subject...
ORGANISM(S): Triticum aestivum 
2019-12-16 | E-MTAB-6140 | biostudies-arrayexpress
TranscriptomicsA time-series transcriptomic changes of Streptococcus mutans in response to heat stress
Dental caries is closely associated with the virulence of Streptococcus mutans (S. mutans). The stress adaptation of S. mutans in the fluctuating oral environment is critical to the virulence expression of this bacterium. Here we used whole-genome microarrays to profile the dynamic transcriptomic re...
ORGANISM(S): Streptococcus mutans UA159 
2014-10-01 | E-GEOD-59302 | biostudies-arrayexpress
UnknownTwo novel heat-soluble protein families abundantly expressed in an anhydrobiotic tardigrade.
Not available
S-EPMC3429414 | biostudies-literature
ProteomicsAggregation and disaggregation features of the human proteome
The aim of the project was to quantify protein aggregation and disaggregation in human cells after transient non-lethal heat shock and during recovery. In addition, the non-aggregating proteins were analyzed by two-dimensional proteome profiling to detect changes in thermal stability upon heat shock...
ORGANISM(S): Homo sapiens (Human) 
2020-09-22 | PXD017291 | Pride
Thermal proteome profiling K562 Heat shock Isobarquant Protein quality control Thermal stability Q exactive plus orbitrap Orbitrap fusion lumos Lc-msms Tmt Disaggregation Silac Human Aggregation Hyperplexing 
TranscriptomicsTranscription profiling of Arabidopsis mature leaves were infiltrated with AZC or L-Proline (control of AZC) and tunicamycin or DMF(solvent control of tunicamycin) to investigate plant response to misfolded protein in the cytosol
Virus infection and over expression of protein in cytosol induce a subset of HSP70s. We named this response the Cytosolic Protein Response (CPR) and have been investigating it in the context of a parallel mechanism in the soluble cytosol with the UPR, and as a subcomponent of the larger HS response....
ORGANISM(S): Arabidopsis thaliana 
2009-01-13 | E-GEOD-11758 | biostudies-arrayexpress
UnknownMultiomics study of a heterotardigrade, Echinisicus testudo, suggests the possibility of convergent evolution of abundant heat-soluble proteins in Tardigrada.
Not available
S-EPMC8582207 | biostudies-literature
TranscriptomicsHeat, Cold and Stress adaptation in Potato
Potato seedlings were subjected to cold, heat and salt stress. Expression profiles were captured at three different time-points, 3h, 9h and 27h from two different tissues, roots and leaves. The experiment was preformed independently three times. Commercially available true potato seeds (Variety Gilr...
ORGANISM(S): Solanum tuberosum 
2010-06-10 | E-GEOD-2416 | biostudies-arrayexpress
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