In the face of escalating challenges posed by infections with multiple drug-resistant (MDR) pathogens, the use of bacteriophages in therapeutic applications has emerged as a critically relevant and often sole alternative to traditional antibiotics. The most promising results of phage therapy have be...
Staphylococcus phage 812, strain K1/420, is a broad-acting bacteriophage infecting S. aureus. Phage 812 belongs to the family Herelleviridae and is closely related to kayviruses. We conducted a structural study of the viral particle of phage 812 before and after genome ejection. We characterized the...
