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MetabolomicsPlasmid-encoded toxin defence mediates mutualistic microbial interactions

Gut environments harbour dense microbial ecosystems in which plasmids are widely distributed. Plasmids facilitate the exchange of genetic material among microorganisms while enabling the transfer of a diverse array of accessory functions. However, their precise impact on microbial community compo...

2023-08-10 | MTBLS7248 | MetaboLights
ProteomicsInvestigating N-terminal shedding of GPR125 in GPR125 overexpressing HEK293T cells using N- and C-terminal enrichment and different cleavage strategies
The study was conducted to elucidate potential cleavage sites of GPR125 which are known to undergo N-terminal shedding through autoproteolysis in a region different to other GRPs. To do these different enzymatic strategies as well as enrichment of both N-terminal and C-terminal peptides, was conduct...
ORGANISM(S): Homo sapiens (Human) 
2026-08-31 | PXD083139 | Pride
Gpr125 Scx C-terminal Lysate Hek293t Enrichment Lc-msms Adra3 N-terminal Medium 
ProteomicsNCLX proximity biotinylation screen
The mitochondrial sodium/calcium exchanger, NCLX, is critical to maintaining mitochondrial calcium homeostasis, yet little remains known about the mechanisms regulating its function. Here, we performed proximity biotinylation screening to identify the NCLX interactome and potential protein regulator...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000093004 | MassIVE
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