Sort   by:  
 Page size 
ProteomicsUHMK1 is a novel splicing regulatory kinase
The U2AF Homology Motif Kinase 1 (UHMK1) is the only kinase that contains the U2AF homology motif (UHM), a common protein interaction domain among splicing factors. Through this motif, UHMK1 interacts with the splicing factors SF1 and SF3B1, known to participate in the 3’ splice site recognition and...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-02 | PXD033353 | Pride
Lc-msms Tmt6 Nih3t3 Phosphoproteomics Mouse 
UnknownAge-related hearing loss in healthy older adults is associated with arterial stiffening and higher aortic systolic blood pressure: potential role of inflammation.
Not available
S-EPMC12932603 | biostudies-literature
UnknownPhosphoSitePlus, 2014: mutations, PTMs and recalibrations.
Not available
S-EPMC4383998 | biostudies-literature
ProteomicsGlobal post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling
Viruses must effectively remodel host cellular pathways to replicate and evade immune defenses, and they must do so with limited genomic coding capacity. Targeting post-translational modification (PTM) pathways provides a mechanism by which viruses can broadly and rapidly transform a hostile host en...
ORGANISM(S): Homo sapiens (Human) 
2022-04-14 | PXD032085 | Pride
Hiv-1 Proteomics Vif B56 Ubiquitination Vpr Pp2a Phosphorylation Histone h1 Systems biology 
UnknownClustergrammer, a web-based heatmap visualization and analysis tool for high-dimensional biological data.
Not available
S-EPMC5634325 | biostudies-literature
ProteomicsCell rearrangement during angiogenesis requires suppression of actomyosin at cell-cell contacts via PI3-kinase.
Sprouting angiogenesis is a highly dynamic process which relies on the continuous interchange of endothelial cell relative position within the vascular sprout, a process mediated by cell rearrangements. Here we take advantage of a previous identified role of p110a/PI3K regulating endothelial cell mo...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-02 | PXD007060 | Pride
Mascot Pescal Phosphoproteomics Qexactive-plus Mice 
UnknownA Hotspot Phosphorylation Site on SHP2 Drives Oncoprotein Activation and Drug Resistance.
Not available
S-EPMC12262427 | biostudies-literature
UnknownA Hotspot Phosphorylation Site on SHP2 Drives Oncoprotein Activation and Drug Resistance.
Not available
S-EPMC12340909 | biostudies-literature
ProteomicsAdaptative changes in protein expression and lysine acetylation induced by decreased glutathione levels in astrocytes
Astrocytes and neurons form a highly specialized functional unit and the loss or gain of astrocytic functions can influence the initiation and progression of different neurodegenerative diseases. Neurons depend on the antioxidant protection provided by neighboring astrocytes. Glutathione (-l-glutamy...
ORGANISM(S): Mus musculus (Mouse) 
2015-10-24 | PXD001834 | Pride
Acetyl Astrocytes Silac 
UnknownPhosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivation.
Not available
S-EPMC3311107 | biostudies-literature
Sort   by:  
 Page size