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We performed a mass spectrometry-based proteomic analysis of normal and malignant prostate tissues from 22 men who underwent surgery for prostate cancer. Prostate cancer samples included Grade Groups (3 to 5), with 8 patients experiencing recurrence and 14 without evidence of recurrence with a mean ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-04 | PXD028118 | Pride
Quantitative proteomics analysis was performed on patient derived neuroendocrine tissue xenografts comparing sh control (N=2), and shUCHL1 (N=4), and in NCI-H660 cell line xenografts comparing control (N=3) and LDN-57444 treated (N=3). Each condition was injected in triplicate.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2023-12-03 | PXD044864 | Pride
We performed shotgun protoemic analysis of tumor samples from HCC1806 shCtrl and shTrop2 xenograft mice.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2021-12-19 | PXD028335 | Pride
Shotgun proteomic analysis of LNCaP-Trop2-OV tumor xenografts and LNCaP-RFP control tumors
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-01-05 | PXD039272 | Pride
We tested a novel small molecule, SU086, as a therapeutic strategy for advanced prostate cancer. Proteomic analysis was performed on treated cell lines and controls to identify protein differences. Cellular thermal shift assay (CETSA) was used to determine the interaction of SU086 with proteins.
ORGANISM(S): Homo sapiens (Human) 
2022-04-01 | PXD030524 | Pride
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