Sort   by:  
 Page size 
Proteomics13C6-Lysine-labelled mouse serum N-terminomics
To investigate the putative lifetime of proteolytically cleaved protein fragments in mouse serum, wildtype mice were fed with 13C6-Lysine for 1 or 2 weeks and the incorporation of 13C6-Lysine into proteins/protein fragments was investigated to achieve lifetime estimations for the fragment(s') genera...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-12 | PXD051273 | Pride
Mouse Serum Hunter Degradome N-termini 13c6-lysine 
ModelsRehm2006_Caspase
This is the standard model described in the article: Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein. Rehm M, Huber HJ, Dussmann H, Prehn JH. EMBO J. 2006 Sep 20;25(18):4338-49. Epub 2006 Aug ...
2024-09-02 | BIOMD0000000256 | BioModels
ProteomicsLC MS/MS of kidney organoids during differentiation from day 21 to 29
Kidney organoids are a valuable and innovative model to understand genetic diseases, kidney development and transcriptomic dynamics. However, their proteome has not been analyzed so far. Here, we analyzed the organoid proteome trajectory during differentiation. Genes involved in podocytopathies and ...
ORGANISM(S): Homo sapiens (Human) 
2023-05-12 | PXD029716 | Pride
Shotgun lc ms/ms Differentiation Maturation Human kidney organoids 
ProteomicsProteome analysis of kidney organoid cells during TNFa stimulation
Kidney organoids are a valuable and innovative model to understand genetic diseases, kidney development and transcriptomic dynamics. However, their proteome has not been analyzed so far. Here, we analyzed the organoid proteome after treatment of organoids with 5ng/mL TNFalpha for 24h and 48h compare...
ORGANISM(S): Homo sapiens (Human) 
2023-05-12 | PXD029718 | Pride
Tnfalpha Cytokine Shotgun lc ms/ms Human kidney organoids Tnfa 
ProteomicsProteomic analysis of kidney organoid supernatant during TNFa stimulation
Kidney organoids are a valuable and innovative model to understand genetic diseases, kidney development and transcriptomic dynamics. However, their proteome has not been analyzed so far. Here, we analyzed the organoid proteome after treatment of organoids with 5ng/mL TNFalpha for 24h and 48h compare...
ORGANISM(S): Homo sapiens (Human) 
2023-05-12 | PXD029696 | Pride
Tnfalpha Cytokine Shotgun lc ms/ms Human kidney organoids Tnfa 
ProteomicsThe ER-SURF pathway uses ER-mitochondria contact sites for protein targeting to mitochondria - Data Set 2
Most mitochondrial proteins are synthesized on cytosolic ribosomes and imported into mitochondria in a post-translational reaction. Mitochondrial precursor proteins which use the ER-SURF pathway employ the surface of the endoplasmic reticulum (ER) as an important sorting platform. How they reach the...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-03-05 | PXD044368 | Pride
Contact sites. endoplasmic reticulum. ermes. er-surf. protein import. protein targeting. mitochondria 
ModelsDallePezze2012 - TSC-independent mTORC2 regulation
DallePezze2012 - TSC-independent mTORC2 regulation This model is described in the article: A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation. Dalle Pezze P, Sonntag AG, Thien A, Prentzell MT, Gödel M, Fischer S, Neumann-Haefelin E, Huber TB, B...
2024-09-02 | BIOMD0000000581 | BioModels
ProteomicsMitoStores: Chaperone-controlled protein granules store mitochondrial precursors in the cytosol - Data Set 2: Hsp104 AP-MS
Hundreds of mitochondrial precursor proteins are synthesized in the cytosol and imported into mitochondria in a post-translational reaction. The early stages in mitochondrial protein targeting are poorly understood. Here we show that in baker’s yeast, the cytosol has the capacity to transiently stor...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-15 | PXD035762 | Pride
Mitostores Mitochondrial import Hsp104 
ProteomicsMitoStores: Chaperone-controlled protein granules store mitochondrial precursors in the cytosol - Data Set 1: Global Proteome TMT
Hundreds of mitochondrial precursor proteins are synthesized in the cytosol and imported into mitochondria in a post-translational reaction. The early stages in mitochondrial protein targeting are poorly understood. Here we show that in baker’s yeast, the cytosol has the capacity to transiently stor...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-01-17 | PXD035760 | Pride
Mitochondrial import Ubiquitin proteasome system Rpn4 Mitostore 
ProteomicsAnalysis of the urinary proteome of mice with and without VPS34 knockout
We analyzed the effect of tubular VPS34 knockout on the urinary proteome.
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD007106 | Pride
Autophagy Mouse Kidney Proximal tubule Urine 
Sort   by:  
 Page size