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TranscriptomicsRNA-seq of the three anatomical regions (reflected, placental and umbilical) of the amniotic membrane in the fetal annexes at term
Identify differentially expressed genes between the different anatomical regions of the human amnion tissue (placental amnion, reflected amnion, and umbilical amnion).
ORGANISM(S): Homo sapiens 
2026-05-29 | E-MTAB-17092 | biostudies-arrayexpress
ProteomicsA multidimensional proteomic strategy for the characterization of the human amnion proteome
The loss of fetal membrane (FM) integrity and function in early pregnancy can have devastating consequences for the fetus and the newborn. However, the current fragmentary knowledge of FM biology has largely hampered the development of preventive FM sealing and healing strategies. Here, by an optimi...
ORGANISM(S): Homo sapiens (Human) 
2021-11-04 | PXD019410 | Pride
Fetal membranes Proteomics Amnion Human proteome Extracellular matrix 
TranscriptomicsTranscription profiling of human amniotic fluid after `amnion treatment with surfactant protein-A
We investigated a potential role for SP-A in human pregnancy and parturition by examining SP-A expression patterns in amniotic fluid and the amnion
ORGANISM(S): Homo sapiens 
2010-04-12 | E-TABM-741 | biostudies-arrayexpress
ProteomicsMatrisome proteins of human and porcine cornea and amnion
In this project, for the first time, the Extracellular Matrix protein compositions of porcine cornea and human amnion (amniotic membrane) were characterized using LC/MS-MS based on an already developed protocol, "Matrisome Project".
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2021-05-21 | PXD020606 | Pride
Porcine cornea Matrisome Proteomics Human amnion 
TranscriptomicsGene expression analysis of human amnion mesenchymal cells treated with dexamethasone
Analysis of cultured human amnion mesenchymal cells treated with synthetic glucocorticoid dexamethasone for 48 hours. Results provide insight into the molecular response of the human amnion to glucocorticoids.
ORGANISM(S): Homo sapiens 
2022-09-09 | E-MTAB-9493 | biostudies-arrayexpress
TranscriptomicsHuman amnion and chondrosarcoma
Cellular differentiation and lineage commitment are considered to be robust and irreversible processes during development. Recent work has shown that mouse and human fibroblasts can be reprogrammed to a pluripotent state with a combination of four transcription factors. This raised the question of w...
ORGANISM(S): Homo sapiens 
2011-06-07 | E-GEOD-29745 | biostudies-arrayexpress
TranscriptomicsExpression data from human amnion mesenchymal cells treated with interleukin-1-beta for 1hr and 8hr
Premature birth continues to be a challenging pregnancy complication, and a body of literature indicates that inflammation can contribute to premature delivery by converting a receptive uterine environment to a hostile one. Cytokines have been demonstrated to provoke up-regulation of inflammatory g...
ORGANISM(S): Homo sapiens 
2011-06-02 | E-GEOD-26315 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human amnion epithelial FL cells treated with the carcinogen BPDE at low concentration
The environmental carcinogen, (±)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide (BPDE), causes bulky-adduct DNA damages, triggers certain signaling pathways, and elicits gene expression changes. Here, we focused on the temporal gene expression changes induced by a low concentration (0.05 µM) BPDE in hum...
ORGANISM(S): Homo sapiens 
2009-01-14 | E-GEOD-10979 | biostudies-arrayexpress
ProteomicsProteomic profie of S100A9-immunoprecipitation
proteomic profie of S100A9-immunoprecipitation in human amnion fibroblasts
ORGANISM(S): Homo Sapiens 
2024-08-09 | PXD054794 |
TranscriptomicsTranscription profiling of human amnion epithelial FL cells treated with benzo(a)pyrene diol epoxide
Genotoxic agents cause cellular DNA damage and stress responses, including transcriptional changes. Here we focused on the early transcriptional responses of human cells to benzo(a)pyrene diol epoxide (BPDE), which causes bulky DNA adduct damage. Human amnion epithelial FL cells were exposed to thre...
ORGANISM(S): Homo sapiens 
2008-04-08 | E-GEOD-7675 | biostudies-arrayexpress
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