Sort   by:  
 Page size 
ProteomicsThe proteome of human iris
The iris is a fine structure that controls the amount of light that enters the eye. Iris diseases that result in visual disability and blindness include iritis, primary angle closure glaucoma, and pigment dispersion syndrome. A detailed investigation of the proteome of the normal human iris may prov...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-29 | MSV000081765 | MassIVE
ProteomicsThe proteome of human iris - Defining the proteome of human iris, ciliary body, retinal pigment epithelium, and choroid
The iris is a fine structure that controls the amount of light that enters the eye. Iris diseases that result in visual disability and blindness include iritis, primary angle closure glaucoma, and pigment dispersion syndrome. A detailed investigation of the proteome of the normal human iris may prov...
ORGANISM(S): Homo sapiens (Human) 
2016-07-18 | PXD001424 | Pride
Iris Proteome Selenoprotein Complement Melanosome Eye 
ProteomicsThe proteome of normal human iris, ciliary body, retinal pigment epithelium, and choroid
The iris is a fine structure that controls the amount of light that enters the eye. The ciliary body controls the shape of the lens and produces aqueous humor. The retinal pigment epithelium and choroid (RPE/choroid) are essential in supporting the retina and absorbing light energy that enters the e...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-29 | MSV000081766 | MassIVE
ProteomicsPrimary angle closure glaucoma is characterized by altered extracellular matrix homeostasis in the iris
Purpose. To characterize the proteome of the iris in primary angle closure glaucoma (PACG). Experimental Design. In this cross-sectional study, iris samples were obtained from surgical iridectomy of 48 adults with PACG and five normal controls. Peptides from iris were analyzed using liquid chromatog...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD022292 | Pride
Eye Proteomics Primary angle closure glaucoma Iris Extracellular matrix 
ProteomicsThe proteome of normal human iris, ciliary body, retinal pigment epithelium, and choroid
The iris is a fine structure that controls the amount of light that enters the eye. The ciliary body controls the shape of the lens and produces aqueous humor. The retinal pigment epithelium and choroid (RPE/choroid) are essential in supporting the retina and absorbing light energy that enters the e...
ORGANISM(S): Homo sapiens (Human) 
2016-02-04 | PXD002194 | Pride
Eye Ciliary body Choroid Iris Retinal pigment epithelium 
ProteomicsA proteomic map of human iris tissue
The human iris tissue is a thin, circular structure in the eye and it is made up of a pigmented epithelial structure. It is a protected internal organ of the eye, located behind the cornea and the aqueous humour. Iris serves main function to control the diameter, size of the pupil and regulation of ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-23 | PXD001299 | Pride
Human iris Brplc Eye proteome Vision 
TranscriptomicsMicroarray analysis of iris gene expression in mice with mutations relevant to glaucoma
Several ocular diseases involve the iris, notably including oculocutaneous albinism, pigment dispersion syndrome, and exfoliation syndrome. To screen for candidate genes that may be active in these diseases, genome-wide iris gene expression patterns were comparatively analyzed from mouse models of t...
ORGANISM(S): Mus musculus 
2010-07-30 | E-GEOD-16994 | biostudies-arrayexpress
MetabolomicsNMR-Based Metabolomics of Non-Human Primate Ocular Tissues: A Dataset
Model animals are employed in experiments as substitutes for human tissues and fluids, particularly when accessing particular human samples (such as cerebrospinal fluid, brain, ocular tissues, etc.) poses significant challenges or is ethically constrained. Nonhuman primates are frequently regarded a...
2023-11-16 | MTBLS8943 | MetaboLights
TranscriptomicsTranscription profiling of mouse T cell response to ocular pigment epithelial cells - role of thrombospondin 1
Ocular pigment epithelium (PE) cells promote the generation of T regulators (PE-induced Treg cells). Moreover, T cells exposed to PE acquire the capacity to suppress the activation of bystander T cells via TGFbeta. Membrane-bound TGFbeta on iris PE cells interacts with TGFbeta receptors on T cells, ...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5134 | biostudies-arrayexpress
TranscriptomicsInduction of IL-17+ T-cells by HIV-Tat protein is mediated via Vascular Endothelial Growth Factor Receptor-2
Anti-retroviral therapy (ART) has transformed human immunodeficiency virus (HIV) infection from a fatal illness to a chronic condition by controlling viral replication and restoring immune function. However, chronic T-cell activation can be observed in 20-35% of individuals on ART, resulting in an i...
ORGANISM(S): Homo sapiens 
2013-08-02 | E-GEOD-44460 | biostudies-arrayexpress
Sort   by:  
 Page size