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ProteomicsLabel free IMS-MSE protein quantification for plant Golgi protein localisation and abundance
Golgi resident proteins in Arabidopsis thaliana are challenging to quantify since the abundance of this organelle is relatively low within the cell. In this study an organelle fractionation approach, targeting the Golgi apparatus, was combined with a label free quantitative MS, data-independent acqu...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2016-07-07 | PXD001056 | Pride
Arabidopsis thaliana Mse Hdmse Lopims Lopit Organelle proteomics Ims-mse Data-independent acquisition Absolute quantitation 
MetabolomicsImidazole ketone erastin induces ferroptosis and slows tumor growth in a mouse lymphoma model
Ferroptosis is a form of regulated cell death that can be induced by inhibition of the cystine-glutamate antiporter, system xc-. Among the existing system xc- inhibitors, imidazole ketone erastin (IKE) is a potent, metabolically stable inhibitor of system xc- and inducer of ferroptosis potentially s...
2019-04-17 | MTBLS774 | MetaboLights
UnknownElectrospray Quadrupole Travelling Wave Ion Mobility Time-of-Flight Mass Spectrometry for the Detection of Plasma Metabolome Changes Caused by Xanthohumol in Obese Zucker (fa/fa) Rats.
Not available
S-EPMC3901285 | biostudies-literature
UnknownSynergizing PIERS and photocatalysis effects in a photo-responsive Ag/TiO<sub>2</sub> nanostructure for an ultrasensitive and renewable PI-PC SERS technique.
Not available
S-EPMC11803388 | biostudies-literature
UnknownOffline two-dimensional liquid chromatography coupled with ion mobility-quadrupole time-of-flight mass spectrometry enabling four-dimensional separation and characterization of the multicomponents from white ginseng and red ginseng.
Not available
S-EPMC7775852 | biostudies-literature
ProteomicsIdentifying mTOR regulated RNA binding proteins
To investigate the RNA binding proteins that change following mTOR inhibition, HeLa cells were treated with and without 200nM Torin1 for an hour. Cells were the UV254 cross-linked, lysed and large scale whole cell oligo(dT) based pulldowns were performed with identification and quantification of pu...
ORGANISM(S): Homo sapiens (Human) 
2020-11-24 | PXD016705 | Pride
Nanoflow. Larp1 Mtor Synapt g2s Rna-binding proteins 
ProteomicsAnalysis of LDL-associated proteins using the method of digitized native protein mapping
The method of digitized native protein mapping, combining nondenaturing micro 2DE, grid gel-cutting and quantitative LC-MS/MS (in data-independent acquisition mode, or MSE), was improved by using a new MS/MS mode, ion mobility separation enhanced-MSE (HDMSE) and applied to analyze the area of human ...
ORGANISM(S): Homo sapiens (Human) 
2016-05-17 | PXD003720 | Pride
Grid gel-cutting Quantitative lc-hdmse Human plasma low-density lipoprotein Protein-protein interactions Nondenaturing micro 2de Digitized native protein mapping 
ProteomicsProteome profile of Perkinsus marinus
Perkinsus marinus is an intracellular parasitic protozoan that is responsible for serious disease epizootics in marine bivalve molluscs worldwide and along with P. olseni belongs to the OIE list of notified diseases. Despite all available information on P. marinus genomics, more baseline data is req...
ORGANISM(S): Perkinsus marinus 
2018-01-08 | PXD003727 | Pride
In vitro culture Virulence Crassostrea rhizophorae Perkinsus marinus Label-free shotgun hdms 
ProteomicsC9ORF72 repeat expansion affects the proteome of primary skin fibroblasts in ALS and FTD
The study design involves the proteomics characterization of primary skin fibroblast cell lines derived from skin biopsies from patients affected by either amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD). Patients enrolled were divided in three groups: 1) ALS patients carrying t...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD023866 | Pride
Human Hdmse Als Fibroblast 
ProteomicsMass spectrometric analyses for the C281-dimedone adduct and the sulfinylated peptide fragments of Orf1
Oxidized cysteine residues are highly reactive and can form functional covalent conjugates, of which the allosteric redox switch formed by the lysine-cysteine NOS bridge is an example. Here, we report a non-canonical FAD-dependent enzyme Orf1 that adds a glycine-derived N-formimidoyl group to glycin...
ORGANISM(S): Escherichia coli 
2023-05-10 | PXD041104 | Pride
N-formimmidolation and iminoacetylation enzyme 
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