Sort   by:  
 Page size 
ProteomicsConvergence of SIRT1 and ATR signaling to modulate replication origin dormancy
SIRT1 chromatin interactome analysis was performed to identify SIRT1 molecular targets involved in replication initiation from cells containing either WT or H363Y SIRT1. Co-IP-MS of pT530 SIRT1 from chromatin extracts was performed. Files are: 1422 WT SIRT1 untreated U2OS; 1423 WT SIRT1 H2O2 treated...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000088103 | MassIVE
ProteomicsATR interactome in Homo sapiens bone osteosarcoma U2OS cells
MS experiments for ATR interactors (GFP-ATR pull-down):SILAC 1,SILAC 2, SILAC 3
ORGANISM(S): Homo sapiens (Human) 
2020-09-30 | PXD020622 | Pride
Interactome atr u2os cells 
ProteomicsTemporal modulation of the NF-kB network in response to different types of DNA damage HYDROXYUREA C4PR_LIV
Different types of DNA damage can initiate phosphorylation-mediated signalling cascades that result in stimulus specific pro- or anti-apoptotic cellular responses. Amongst its many roles, the NF-κB transcription factor RelA is central to the DNA damage response pathway. Yet, understanding of the co-...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019589 | Pride
Dna damage  rela  p65  nf-κb  phosphorylation  mass spectrometry Phosphoproteomics  etoposide  hydroxyurea 
ProteomicsTemporal modulation of the NF-kB network in response to different types of DNA damage ETOPOSIDE C4PR_LIV
Different types of DNA damage can initiate phosphorylation-mediated signalling cascades that result in stimulus specific pro- or anti-apoptotic cellular responses. Amongst its many roles, the NF-κB transcription factor RelA is central to the DNA damage response pathway. Yet, understanding of the co-...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019587 | Pride
Dna damage  rela  p65  nf-κb  phosphorylation  mass spectrometry Phosphoproteomics  etoposide  hydroxyurea 
UnknownTemporal modulation of the NF-κB RelA network in response to different types of DNA damage.
Not available
S-EPMC7886319 | biostudies-literature
ProteomicsMYC multimers shield stalled replication forks from RNA polymerase
Oncoproteins of the MYC family drive the development of numerous human tumors. In unperturbed cells, MYC proteins bind to virtually all active promoters and control transcription by RNA Polymerase II (RNAPII). MYC proteins can also coordinate transcription with DNA replication and promote the repair...
ORGANISM(S): Homo sapiens (Human) 
2022-10-27 | PXD036674 | Pride
Brca1 Dsbs Rnapii Myc Replication fork Fancd2 Multimerization Antisense transcription Huwe1 
Sort   by:  
 Page size