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We applied SD-SILAC to determine absolute acetylation stoichiometry in exponentially-growing and stationary-phase wild type and sirtuin deacetylase CobB-deficient E. coli. We further assayed stoichiometry in phophotransacetylase (pta) and acetate kinase (ackA) mutant strains in the presence and abse...
ORGANISM(S): Escherichia coli 
2017-03-07 | PXD005757 | Pride
Highly quantitative biomarkers of neurodegenerative disease remain an important need in the urgent quest for disease modifying therapies. For Huntington's disease (HD), a genetic test is available (trait marker), but necessary state markers are still in development. In this report, we describe a lar...
ORGANISM(S): Homo sapiens 
Heritable epigenetic variation in wild and domesticated chickens. Original processed data are available in the archive: http://www.ebi.ac.uk/arrayexpress/files/E-MTAB-645/E-MTAB-645.additional.zip
ORGANISM(S): Gallus gallus 
Heritable epigenetic variation in wild and domesticated chickens. Original processed data are available in the archive: http://www.ebi.ac.uk/arrayexpress/files/E-MTAB-644/E-MTAB-644.additional.zip
ORGANISM(S): Gallus gallus 
Mechanosensing is required for the senses of touch and hearing, and impacts on cellular processes such as cell differentiation, migration, invasion and tissue homeostasis. Mechanical inputs give rise to p38- and JNK-signaling, which mediates adaptive physiological responses in various tissues. In mu...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-31 | PXD028548 | Pride
Long non-coding RNAs (lncRNAs) play important roles in the regulation of many biological processes in the cell like transcription, translation, splicing, transport, etc. More than 10K lncRNAs are predicted in human, but functions for the majority remain unknown. LncRNAs may contribute to the develop...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-11 | PXD033910 | Pride
The aim of the study was to decipher metabolisms responsible (i) for the peculiar adaptation of L. plantarum during soy juice fermentation and (ii) for the release of aroma compounds, amino and short-chain fatty acid, and metabolites with health-promoting properties in soy yogurt. The strategy was t...
ORGANISM(S): Lactiplantibacillus plantarum 
Investigation of the bovine mammary gland response to Escherichia coli and Staphylococcus aureus infection. The aims of the study were to examine the dynamics of the mammary gland response to pathogen invasion and identify general and pathogen-specific transcriptional profiles. Individual udder qu...
ORGANISM(S): Bos taurus 
The oncoprotein survivin, coded by BIRC5 gene has been shown to bind to chromatin. Chromatin immunoprecipitation of stimulated CD4+ T cells with survivin has been published (GSE190354). The role of survivin in transcriptional regulation acting in synergy with transcription factor complexes has been ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD049683 | Pride
There is a need to discover and develop non-toxic antibiotics that are effective against metabolically dormant bacteria, which underlie chronic infections and promote antibiotic resistance. Traditional antibiotic discovery has historically favored compounds effective against actively metabolizing ce...
ORGANISM(S): Escherichia coli 
2023-08-21 | PXD044230 | Pride
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