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MetabolomicsEnterococcus faecalis JM263 Alleviates Liver Metabolomics Perturbations in Yaks Fed a High-concentrate Diet

This study employs untargeted metabolomics (LC-MS/MS) to investigate the metabolic reprogramming in the liver of yaks in response to Enterococcus faecalis JM263 supplementation under a high-concentrate diet (HCD). Yaks were divided into a control group (HCD) and a treatment group (HCD + E. faecal...

2026-01-08 | MTBLS13640 | MetaboLights
ProteomicsAn extracellular receptor tyrosine kinase motif orchestrating intracellular STAT activation
The ErbB4 receptor isoforms JM-a and JM-b differ within their extracellular juxtamembrane (eJM) domains. Here, ErbB4 isoforms are used as a model to address the effect of structural variation in the eJM domain of receptor tyrosine kinases (RTK) on downstream signaling. A specific JM-a-like sequence ...
ORGANISM(S): Homo sapiens (Human) 
2023-01-30 | PXD026546 | Pride
Receptor tyrosine kinase Jm-a Rtk Stat signaling Erbb4 Jm-b 
UnknownEnrichment of Anaerobic Syngas-Converting Communities and Isolation of a Novel Carboxydotrophic Acetobacterium wieringae Strain JM.
Not available
S-EPMC7006291 | biostudies-literature
UnknownNeonatal administration of a subanaesthetic dose of JM-1232(-) in mice results in no behavioural deficits in adulthood.
Not available
S-EPMC8213711 | biostudies-literature
UnknownChemical Synthesis, Pharmacokinetic Properties and Biological Effects of JM-00266, a Putative Non-Brain Penetrant Cannabinoid Receptor 1 Inverse Agonist.
Not available
S-EPMC8949893 | biostudies-literature
ProteomicsSTAT5b is a key effector of NRG-1/ERBB4-mediated cardiomyocyte growth
Interactome of ErbB4 JM-a and JM-b in MDA-MB-468 cells.
ORGANISM(S): Homo sapiens (Human) 
2023-02-20 | PXD040166 | Pride
Stat5 Interactome Erbb4 Nrg-1 Lc-msms Cardiomyocyte 
UnknownOverexpression of ERBB4 JM-a CYT-1 and CYT-2 isoforms in transgenic mice reveals isoform-specific roles in mammary gland development and carcinogenesis.
Not available
S-EPMC4303208 | biostudies-literature
UnknownIdentification and phylogenetic analysis of Japanese Macaque Babesia-1 (JM-1) detected from a Japanese Macaque (Macaca fuscata fuscata).
Not available
S-EPMC3183768 | biostudies-literature
MetabolomicsThe ULK3 kinase is a key determinant of keratinocyte self-renewal and tumorigenesis targeting the arginine methylome
Epigenetic mechanisms oversee epidermal homeostasis and oncogenesis. The identification of kinases controlling these processes has direct therapeutic implications. We show that ULK3 is a nuclear kinase with elevated expression levels in squamous cell carcinomas (SCCs) arising in multiple body sites,...
2022-11-14 | MTBLS5155 | MetaboLights
ProteomicsTargeted validation of interaction between ErbB4 JM-a isoform and β1 integrin
The ErbB4 receptor isoforms JM-a and JM-b differ within their extracellular juxtamembrane (eJM) domains. Here we used ErbB4 isoforms as a model to address whether structural variation in the eJM domain of receptor tyrosine kinases (RTK) affects downstream signaling. Analysis of ErbB4 interactome and...
ORGANISM(S): Homo Sapiens 
2022-10-22 | PXD026617 | panorama
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